The intracellular signal for induction of resistance to alkylating agents in E. coli

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

1985 • 1,025 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

IN VITRO SYNTHESIS OF PROTEIN IN MICROBIAL SYSTEMS

1973 • 675 citations

Cyclic AMP Receptor Protein: Role in Transcription Activation

1984 • 645 citations

The htpR gene product of E. coli is a sigma factor for heat-shock promoters

1984 • 593 citations

INDUCIBLE DNA REPAIR SYSTEMS

1985 • 586 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

Inducible repair of oxidative DNA damage in Escherichia coli

1983 • 415 citations

POSITIVE CONTROL OF TRANSCRIPTION INITIATION IN BACTERIA

1984 • 369 citations

Cellular responses to DNA damage

1983 • 301 citations

The interaction of RNA polymerase and lac repressor with the lac control region

1979 • 283 citations

Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1982 • 283 citations

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1977 • 225 citations

Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli.

1984 • 223 citations

Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis.

1985 • 221 citations

Nucleotide sequence of the heat shock regulatory gene of E. coli suggests its protein product may be a transcription factor

1984 • 198 citations

Autoregulation of the dnaA gene of Escherichia coli K12

1985 • 196 citations

Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.

1982 • 172 citations

Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage.

1984 • 162 citations

Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents

1979 • 160 citations

Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein ofE. coli

1985 • 139 citations

Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O⁶-methyiguanine-DNA methyttransferase

1983 • 137 citations

Cloning of theE. coliO⁶-methylguanine and methylphosphotriester methyltransferase gene using a functional DNA repair assay

1985 • 124 citations

Purification and structure of the intact Ada regulatory protein of Escherichia coli K12, O6-methylguanine-DNA methyltransferase.

1985 • 124 citations

Molecular cloning of a gene which regulates the adaptive response to alkylating agents in Escherichia coli

1983 • 110 citations

Structure and expression of the alkA gene of Escherichia coli involved in adaptive response to alkylating agents.

1984 • 98 citations

Cloning and characterization of the alkA gene of Escherichia coli that encodes 3-methyladenine DNA glycosylase II.

1984 • 90 citations

Induction and autoregulation of ada, a positively acting element regulating the response of Escherichia coli K-12 to methylating agents

1985 • 87 citations

Induction of specific Escherichia coli genes by sublethal treatments with alkylating agents.

1984 • 82 citations

O²- and O⁴-Alkyl pyrimidine nucleosides: stability of the glycosyl bond and of the alkyl group as a function of pH

1978 • 74 citations

Cloning of Escherichia coli genes encoding 3-methyladenine DNA glycosylases I and II

1984 • 69 citations

Molecular cloning and characterization of the alkB gene of Escherichia coli

1985 • 66 citations

Stereospecific removal of methyl phosphotriesters from DNA by anEscherichia coli ada⁺extract

1985 • 55 citations

Regulation of expression of the cloned ada gene in Escherichia coli

1985 • 34 citations

E. coli Ada regulatory protein repairs the Sp diastereoisomer of alkylated DNA

1985 • 15 citations

Alkylation and Oxidative Damages to DNA: Constitutive and Inducible Repair Systems

1986 • 13 citations

Molecular Mechanism of Adaptive Response to Alkylating Agents

1986 • 3 citations