Cell adherence to fibronectin and the aggregation of the high affinity immunoglobulin E receptor synergistically regulate tyrosine phosphorylation of 105-115-kDa proteins.

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Integrins.

1991 • 1,369 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

An automated continuous-flow system for the extraction and fluorometric analysis of histamine

1974 • 750 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Paxillin: a new vinculin-binding protein present in focal adhesions.

1990 • 687 citations

Regulated expression and binding of three VLA (β1) integrin receptors on T cells

1990 • 634 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.

1991 • 578 citations

Adhesive recognition sequences

1991 • 571 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1992 • 503 citations

Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin.

1990 • 400 citations

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape.

1991 • 368 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

The mechanism of the calcium signal and correlation with histamine release in 2H3 cells.

1984 • 351 citations

Lymphocyte interactions with extracellular matrix

1991 • 336 citations

Development of cell surface linkage complexes in cultured fibroblasts.

1985 • 320 citations

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.

1991 • 310 citations

Cell surface receptors for extracellular matrix components

1990 • 297 citations

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex.

1989 • 291 citations

Phosphorylation and dephosphorylation of the high-affinity receptor for immunoglobulin E immediately after receptor engagement and disengagement

1991 • 272 citations

Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family.

1991 • 259 citations

Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts.

1989 • 256 citations

Fibronectin promotes proliferation of naive and memory T cells by signaling through both the VLA-4 and VLA-5 integrin molecules.

1990 • 241 citations

Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

1990 • 234 citations

Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytes.

1988 • 230 citations

Membrane and cytoskeletal changes associated with IgE-mediated serotonin release from rat basophilic leukemia cells.

1985 • 224 citations

VLA-4 mediates CD3-dependent CD4+ T cell activation via the CS1 alternatively spliced domain of fibronectin.

1990 • 224 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

IgE-induced tyrosine phosphorylation of phospholipase C-gamma 1 in rat basophilic leukemia cells.

1991 • 184 citations

Tumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+.

1990 • 180 citations

Phorbol ester modulation of integrin-mediated cell adhesion: a postreceptor event.

1989 • 164 citations

Activation of human CD4 T lymphocytes. Interaction of fibronectin with VLA-5 receptor on CD4 cells induces the AP-1 transcription factor.

1991 • 154 citations

Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils.

1990 • 151 citations

Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein.

1992 • 143 citations

Vinculin phosphorylation in response to calcium and phorbol esters in intact cells.

1984 • 130 citations

Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides.

1986 • 128 citations

Suppressor effects and cyclic AMP accumulation by the CD29 molecule of CD4+ lymphocytes

1989 • 109 citations

Adherence of rat basophilic leukemia (RBL-2H3) cells to fibronectin-coated surfaces enhances secretion.

1992 • 94 citations

Activation of phospholipase D in a rat mast (RBL 2H3) cell line. A possible unifying mechanism for IgE-dependent degranulation and arachidonic acid metabolite release.

1991 • 91 citations

High-affinity IgE receptor-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells induces early and late protein-tyrosine phosphorylations.

1992 • 88 citations

Phosphorylation of talin at tyrosine in Rous sarcoma virus-transformed cells.

1987 • 83 citations

Regulation of adhesion of mouse bone marrow-derived mast cells to laminin.

1990 • 73 citations

Fc epsilon RI-induced protein tyrosine phosphorylation of pp72 in rat basophilic leukemia cells (RBL-2H3). Evidence for a novel signal transduction pathway unrelated to G protein activation and phosphatidylinositol hydrolysis.

1992 • 73 citations

Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.

1988 • 69 citations

Antigen- and ionophore-induced signal transduction in rat basophilic leukemia cells involves protein tyrosine phosphorylation.

1991 • 57 citations

Differential tyrosine-specific phosphorylation of integrin in Rous sarcoma virus transformed cells with differing transformed phenotypes.

1990 • 55 citations

IgE-dependent regulation of human basophil adherence to vascular endothelium.

1989 • 55 citations

Phospholipase A2 stimulation during cell secretion in rat basophilic leukemia cells.

1986 • 54 citations

The actions of Ca2+ ionophores on rat basophilic (2H3) cells are dependent on cellular ATP and hydrolysis of inositol phospholipids. A comparison with antigen stimulation.

1987 • 45 citations

Morphological changes induced by the calcium ionophore A23187 in rat basophilic leukemia (2H3) cells.

1990 • 39 citations

Inhibition of IgE binding to RBL-2H3 cells by a monoclonal antibody (BD6) to a surface protein other than the high affinity IgE receptor.

1992 • 13 citations