Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

An automated continuous-flow system for the extraction and fluorometric analysis of histamine

1974 • 750 citations

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

1988 • 716 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

Activation of Mast Cells for Mediator Release through IgE Receptors

2015 • 369 citations

Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets.

1989 • 276 citations

A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical subunit

1989 • 268 citations

A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII

1989 • 189 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

Mechanisms for Regulating Expression of Membrane Isoforms of FcγRIII (CD16)

1989 • 162 citations

Antibody-cell interactions: Fc receptors

1989 • 126 citations

A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.

1989 • 119 citations

Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.

1988 • 113 citations

Monoclonal antibodies that inhibit IgE binding.

1986 • 113 citations

p60c-src activity detected in the chromaffin granule membrane

1986 • 109 citations

Translocation of the FGR protein-tyrosine kinase as a consequence of neutrophil activation.

1989 • 108 citations

Membrane Phosphoinositide-Activated Signals in Mast Cells and Basophils1

2015 • 91 citations

The kinetics of phosphoinositide hydrolysis in rat basophilic leukemia (RBL-2H3) cells varies with the type of IgE receptor cross-linking agent used.

1987 • 79 citations

Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.

1981 • 77 citations

Studies of protein kinase C in the rat basophilic leukemia (RBL-2H3) cell reveal that antigen-induced signals are not mimicked by the actions of phorbol myristate acetate and Ca2+ ionophore.

1989 • 71 citations

Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.

1988 • 69 citations

p60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis.

1988 • 69 citations

The relative contributions of extracellular and intracellular calcium to secretion from tumor mast cells. Multiple effects of the proton ionophore carbonyl cyanide m-chlorophenylhydrazone.

1987 • 61 citations

The control of mediator release from RBL-2H3 cells: roles for Ca2+, Na+, and protein kinase C1.

1987 • 50 citations

Calcium-independent phosphoinositide breakdown in rat basophilic leukemia cells. Evidence for an early rise in inositol 1,4,5-trisphosphate which precedes the rise in other inositol phosphates and in cytoplasmic calcium.

1987 • 48 citations

The receptor for immunoglobulin E: Examination for kinase activity and as a substrate for kinases

1986 • 39 citations

Effect of nonhydrolyzable guanosine phosphate on IgE-mediated activation of phospholipase C and histamine release from rodent mast cells.

1989 • 29 citations

Characterization of monoclonal antibodies produced by immunization with partially purified IgE receptor complexes

1987 • 25 citations

The actin domain of Gardner-Rasheed feline sarcoma virus inhibits kinase and transforming activities

1989 • 11 citations

Role of GTP-binding protein in histamine release from mast cells

1989 • 9 citations