Induction of leukemia-specific cytotoxic response by cross-presentation of late-apoptotic leukemic blasts by autologous dendritic cells of nonleukemic origin.

Dendritic cells and the control of immunity

1998 • 14,345 citations

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Graft-versus-leukemia reactions after bone marrow transplantation

1990 • 2,781 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Antigen-Specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells

2001 • 1,384 citations

Bone Marrow Transplantation for Chronic Myelogenous Leukemia in Chronic Phase

1988 • 887 citations

Dendritic Cells in Cancer Immunotherapy

2000 • 698 citations

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

2000 • 679 citations

Regression of human metastatic renal cell carcinoma after vaccination with tumor cell–dendritic cell hybrids

2000 • 652 citations

Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells

2000 • 544 citations

Idiotype Vaccination Using Dendritic Cells After Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma—A Feasibility Study

1999 • 398 citations

Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity

1997 • 390 citations

Distinctions Between CD8+ and CD4+ T-Cell Regenerative Pathways Result in Prolonged T-Cell Subset Imbalance After Intensive Chemotherapy

1997 • 388 citations

HLA class I-restricted lysis of leukemia cells by a CD8+ cytotoxic T-lymphocyte clone specific for WT1 peptide

2000 • 351 citations

Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells.

2000 • 319 citations

Dendritic Cells Induce Autoimmune Diabetes and Maintain Disease via De Novo Formation of Local Lymphoid Tissue

1998 • 315 citations

Dendritic Cells Retrovirally Transduced with a Model Antigen Gene Are Therapeutically Effective against Established Pulmonary Metastases

1997 • 309 citations

Use of Leukemic Dendritic Cells for the Generation of Antileukemic Cellular Cytotoxicity Against Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia

1997 • 309 citations

Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene ( WT1 ) product

2000 • 250 citations

Cytotoxic T Lymphocytes Specific for a Nonpolymorphic Proteinase 3 Peptide Preferentially Inhibit Chronic Myeloid Leukemia Colony-Forming Units

1997 • 245 citations

Dendritic Cells Derived In Vitro From Acute Myelogenous Leukemia Cells Stimulate Autologous, Antileukemic T-Cell Responses

1999 • 241 citations

Dendritic Cells Capture Killed Tumor Cells and Present Their Antigens to Elicit Tumor-Specific Immune Responses

2000 • 237 citations

T‐Cell Immunodeficiency Following Cytotoxic Antineoplastic Therapy: A Review

2000 • 218 citations

Vaccination of multiple myeloma patients with idiotype‐pulsed dendritic cells: immunological and clinical aspects

2000 • 211 citations

Dendritic cells resurrect antigens from dead cells

2001 • 192 citations

Bone Marrow‐Derived Dendritic Cells Serve as Potent Adjuvants for Peptide‐Based Antitumor Vaccines

1997 • 144 citations

Idiotype vaccination using dendritic cells after autologous peripheral blood progenitor cell transplantation for multiple myeloma

2000 • 144 citations

Dendritic Cells Stimulate the Expansion of bcr-abl Specific CD8+ T Cells With Cytotoxic Activity Against Leukemic Cells From Patients With Chronic Myeloid Leukemia

1998 • 133 citations

Antigen-presenting cells that phagocytose apoptotic tumor-derived cells are potent tumor vaccines.

1999 • 133 citations

Expression of costimulatory molecules in human leukemias.

1996 • 130 citations

CD34+ Acute Myeloid and Lymphoid Leukemic Blasts Can Be Induced to Differentiate Into Dendritic Cells

1999 • 130 citations

Human acute myeloblastic leukemia cells differentiatein vitro into mature dendritic cells and induce the differentiation of cytotoxic T cells against autologous leukemias

1999 • 116 citations

Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia.

1998 • 115 citations

The allogeneic response and tumor immunity

2001 • 103 citations

Stimulation of autologous proliferative and cytotoxic T-cell responses by “leukemic dendritic cells” derived from blast cells in acute myeloid leukemia

2001 • 102 citations

Standardized generation of fully mature p70 IL-12 secreting monocyte-derived dendritic cells for clinical use

2001 • 96 citations

Role of dendritic cells in the induction and maintenance of autoimmune diseases

1999 • 88 citations

Human dendritic cells require multiple activation signals for the efficient generation of tumor antigen-specific T lymphocytes

2000 • 83 citations

Leukemic dendritic cells generated in the presence of FLT3 ligand have the capacity to stimulate an autologous leukemia-specific cytotoxic T cell response from patients with acute myeloid leukemia

2001 • 72 citations

Dendritic cells that process and present nominal antigens to naive T lymphocytes are derived from CD2+ precursors.

1997 • 67 citations

Cytokine‐Driven Differentiation of Blasts from Patients with Acute Myelogenous and Lymphoblastic Leukemia into Dendritic Cells

2000 • 60 citations

Targeting of a B7-1 (CD80) immunoglobulin G fusion protein to acute myeloid leukemia blasts increases their costimulatory activity for autologous remission T cells

2001 • 51 citations

Effect of Costimulation and the Microenvironment on Antigen Presentation by Leukemic Cells

1999 • 51 citations

Membrane-Bound Fas (Apo-1/CD95) Ligand on Leukemic Cells: A Mechanism of Tumor Immune Escape in Leukemia Patients

1999 • 50 citations

Dendritic cells stimulate the expansion of PML-RAR alpha specific cytotoxic T-lymphocytes: its applicability for antileukemia immunotherapy.

1999 • 34 citations

Phenotype, genotype and cytokine production in acute leukemia involving progenitors of dendritic Langerhans' cells

1994 • 30 citations

Clonal chromosomal abnormalities in the stem cell compartment of patients with acute myeloid leukemia in morphological complete remission

1999 • 28 citations

Approaches to Dendritic Cell‐Based Immunotherapy after Peripheral Blood Stem Cell Transplantation

1999 • 27 citations

Culture requirements for induction of dendritic cell differentiation in acute myeloid leukemia

2000 • 25 citations

Induction of antitumor cytotoxic activity using CD34+ cord blood cell-derived and irradiated tumor cell-primed dendritic cells.

1998 • 17 citations

Long-term molecular remission induced by donor lymphocyte infusions for recurrent acute myeloblastic leukemia after allogeneic bone marrow transplantation

2000 • 13 citations