Apoptosis of Late-Stage Erythroblasts in Megaloblastic Anemia: Association With DNA Damage and Macrocyte Production

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

1994 • 2,025 citations

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

1994 • 1,165 citations

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

1995 • 1,114 citations

UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells.

1984 • 874 citations

Erythropoietin Retards DNA Breakdown and Prevents Programmed Death in Erythroid Progenitor Cells

1990 • 837 citations

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1996 • 544 citations

Growth factor modulation of p53-mediated growth arrest versus apoptosis.

1995 • 377 citations

THE SEPARATION OF DIFFERENT CELL CLASSES FROM LYMPHOID ORGANS

1971 • 257 citations

Maintenance by erythropoietin of viability and maturation of murine erythroid precursor cells

1988 • 198 citations

Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells.

1993 • 196 citations

Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation

1991 • 170 citations

Splenic erythroblasts in anemia‐inducing friend disease: A source of cells for studies of erythropoietin‐mediated differentiation

1984 • 146 citations

Cytoskeletal distribution and function during the maturation and enucleation of mammalian erythroblasts.

1989 • 143 citations

2 DNA damage in folate deficiency

1995 • 128 citations

Bone marrow cells from vitamin B12- and folate-deficient patients misincorporate uracil into DNA

1994 • 124 citations

Cytogenetic Observations in Vitamin B12 and Folate Deficiency

1966 • 124 citations

Cytogenetic and Cytochemical Studies on Marrow Cells in B12 and Folate Deficiency

1966 • 99 citations

The separation of different cell classes from lymphoid organs. VI. The effect of osmolarity of gradient media on the density distribution of cells.

1972 • 80 citations

Apoptosis mediates and thymidine prevents erythroblast destruction in folate deficiency anemia.

1994 • 74 citations

Analysis of Uracil in DNA by Gas Chromatography-Mass Spectrometry

1994 • 66 citations

Ineffective hematopoiesis in folate-deficient mice

1992 • 60 citations

Morphological changes in erythroblasts during erythropoietin-induced terminal differentiation in vitro.

1988 • 50 citations

Erythropoietin control of terminal erythroid differentiation: maintenance of cell viability, production of hemoglobin, and development of the erythrocyte membrane.

1987 • 38 citations

Effect of nitrous oxide inactivation of vitamin B12 on the levels of folate coenzymes in rat bone marrow, kidney, brain, and liver

1986 • 25 citations

Metabolic adaptation during erythropoietin-mediated terminal differentiation of mouse erythroid cells

1991 • 22 citations

Megaloblastic Anemias

1985 • 18 citations

Deleted Work

1955 • 0 citations