Localization and subcellular distribution of smg p25A, a ras p21-like GTP-binding protein, in rat brain.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

ras GENES

1987 • 3,818 citations

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

1976 • 1,926 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)

1964 • 1,213 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

A ras-related gene with transformation suppressor activity

1989 • 979 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

A 38,000-dalton membrane protein (p38) present in synaptic vesicles.

1985 • 856 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

Immunochemistry on ultrathin frozen sections

1980 • 755 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections.

1983 • 555 citations

Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.

1983 • 535 citations

The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.

1989 • 500 citations

Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.

1984 • 498 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

A novel ras-related gene family

1985 • 487 citations

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1

1983 • 441 citations

Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.

1987 • 403 citations

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils

1986 • 339 citations

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

1988 • 334 citations

The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide

1989 • 293 citations

Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line.

1983 • 290 citations

ISOLATION AND STRUCTURAL STUDIES ON SYNAPTIC COMPLEXES FROM RAT BRAIN

1972 • 267 citations

The ral gene: a new ras related gene isolated by the use of a synthetic probe.

1986 • 264 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25,000 from bovine brain.

1988 • 234 citations

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

1987 • 216 citations

Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes.

1988 • 207 citations

Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins.

1988 • 204 citations

Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.

1979 • 200 citations

Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis.

1987 • 197 citations

A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes. Purification, determination of primary structure, and characterization.

1988 • 185 citations

Nucleotide sequence of human rho cDNA clone 12

1987 • 143 citations

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

1987 • 142 citations

Coding sequence of humanrhocDNAs clone 6 and clone 9

1988 • 137 citations

Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues.

1988 • 105 citations

Guanine nucleotide-binding proteins that enhance choleragen ADP-ribosyltransferase activity: nucleotide and deduced amino acid sequence of an ADP-ribosylation factor cDNA.

1988 • 99 citations

Control of exocytosis

1987 • 98 citations

Purification and characterization of a GTP-binding protein with a molecular weight of 20,000 in bovine brain membranes. Identification as the rho gene product.

1988 • 93 citations

Tissue distribution of smg p25A, a ras p21-like GTP-binding protein, studied by use of a specific monoclonal antibody

1989 • 84 citations

Tissue-specific expression of a novel GTP-binding protein (smg p25A) mRNA and its increase by nerve growth factor and cyclic AMP in rat pheochromocytoma PC-12 cells

1989 • 79 citations

Role of protein kinase C in transmembrane signaling

1985 • 76 citations

Complete coding sequences of therasrelatedrab3 and 4 cDNAs

1988 • 65 citations

Localization and subcellular distribution of cellular ras gene products in rat brain

1989 • 56 citations

Intrasynaptosomal distribution of the ras, rho and smg-25A GTP-binding proteins in bovine brain

1989 • 42 citations

Purification and characterization of c-Ki-ras p21 from bovine brain crude membranes.

1988 • 42 citations

Purification and characterization from bovine brain membranes of a GTP-binding protein with a Mr of 21,000, ADP-ribosylated by an ADP-ribosyltransferase contaminated in botulinum toxin type C1 4- Identification as the rhoA gene product

1990 • 37 citations

Multiple small molecular weight gtp-binding proteins in bovine brain cytosol purification and characterization of a 24KDa protein

1988 • 26 citations