Intrasynaptosomal distribution of the ras, rho and smg-25A GTP-binding proteins in bovine brain

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

ras GENES

1987 • 3,818 citations

The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)

1964 • 1,213 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

A ras-related gene with transformation suppressor activity

1989 • 979 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1985 • 738 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.

1986 • 533 citations

A novel ras-related gene family

1985 • 487 citations

Molecular Pharmacology of Botulinum Toxin and Tetanus Toxin

1986 • 469 citations

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

1985 • 458 citations

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

1986 • 421 citations

Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.

1987 • 403 citations

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils

1986 • 339 citations

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

1988 • 334 citations

ISOLATION AND STRUCTURAL STUDIES ON SYNAPTIC COMPLEXES FROM RAT BRAIN

1972 • 267 citations

The ral gene: a new ras related gene isolated by the use of a synthetic probe.

1986 • 264 citations

Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25,000 from bovine brain.

1988 • 234 citations

Expression of ras proto-oncogene proteins in normal human tissues.

1987 • 216 citations

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

1987 • 216 citations

Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes.

1988 • 207 citations

Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins.

1988 • 204 citations

Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase.

1979 • 200 citations

A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes. Purification, determination of primary structure, and characterization.

1988 • 185 citations

Substrate for botulinum ADP-ribosyltransferase, Gb, has an amino acid sequence homologous to a putative rho gene product.

1988 • 178 citations

GTP-binding proteins: One molecular machine can transduce diverse signals

1986 • 157 citations

Nucleotide sequence of human rho cDNA clone 12

1987 • 143 citations

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

1987 • 142 citations

Purification of the 22 kDa protein substrate of botulinum ADP‐ribosyltransferase C3 from porcine brain cytosol and its characterization as a GTP‐binding protein highly homologous to the rho gene product

1989 • 139 citations

A carboxyl-terminal cysteine residue is required for palmitic acid binding and biological activity of the ras-related yeast YPT1 protein.

1988 • 138 citations

Coding sequence of humanrhocDNAs clone 6 and clone 9

1988 • 137 citations

ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1.

1988 • 126 citations

Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues.

1988 • 105 citations

Small Molecular Weight GTP-binding Proteins in Human Platelet Membranes

1989 • 100 citations

Guanine nucleotide-binding proteins that enhance choleragen ADP-ribosyltransferase activity: nucleotide and deduced amino acid sequence of an ADP-ribosylation factor cDNA.

1988 • 99 citations

Inhibition of exocytosis in bovine adrenal medullary cells by botulinum toxin type D

1985 • 96 citations

Induction of Neurite Formation in PC12 Cells by Microinjection of Proto-Oncogenic Ha-ras Protein Preincubated with Guanosine-5′-O-(3-Thiotriphosphate)

1987 • 95 citations

Purification and characterization of a GTP-binding protein with a molecular weight of 20,000 in bovine brain membranes. Identification as the rho gene product.

1988 • 93 citations

Purification and properties of the cytosolic substrate for botulinum ADP-ribosyltransferase. Identification as an Mr 22,000 guanine nucleotide-binding protein.

1988 • 84 citations

Tissue-specific expression of a novel GTP-binding protein (smg p25A) mRNA and its increase by nerve growth factor and cyclic AMP in rat pheochromocytoma PC-12 cells

1989 • 79 citations

Role of protein kinase C in transmembrane signaling

1985 • 76 citations

Identification and purification from bovine brain of a guanine-nucleotide-binding protein distinct from Gs, Gi and Go

1987 • 69 citations

Complete coding sequences of therasrelatedrab3 and 4 cDNAs

1988 • 65 citations

Induction of neurite formation in PC12 cells by microinjection of proto-oncogenic Ha-ras protein preincubated with guanosine-5'-O-(3-thiotriphosphate).

1987 • 59 citations

Localization and subcellular distribution of cellular ras gene products in rat brain

1989 • 56 citations

Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products

1988 • 52 citations

Purification and characterization of c-Ki-ras p21 from bovine brain crude membranes.

1988 • 42 citations

Multiple small molecular weight gtp-binding proteins in bovine brain cytosol purification and characterization of a 24KDa protein

1988 • 26 citations

Purification and characterization of two GTP‐binding proteins of 22 kDa from human platelet membranes

1988 • 25 citations