Back to search

Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin

Data up to Jan 2025

Published2004
Citations185
References49

Total Citations Per Year

Abstract

References (49)

Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System

2001 • 1,678 citations

NG2-Positive Oligodendrocyte Progenitor Cells in Adult Human Brain and Multiple Sclerosis Lesions

2000 • 686 citations

PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine

1995 • 656 citations

Psychomotor stimulant addiction: a neural systems perspective.

2002 • 635 citations

Age-Related Changes in Frontal and Temporal Lobe Volumes in Men

2001 • 630 citations

Psychomotor Stimulant Addiction: A Neural Systems Perspective

2002 • 573 citations

Impaired inhibitory control of behavior in chronic cocaine users

2002 • 518 citations

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

2001 • 393 citations

Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis

1989 • 386 citations

Cerebral Blood Flow in Chronic Cocaine Users: A Study with Positron Emission Tomography

1988 • 368 citations

Molecular alterations in the neostriatum of human cocaine addicts

1993 • 326 citations

Tissue pH as an indicator of mRNA preservation in human post-mortem brain

1995 • 318 citations

Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics

2002 • 318 citations

Cocaine dependence: a disease of the brain’s reward centers

2001 • 314 citations

Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat

1997 • 282 citations

Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

2002 • 278 citations

Cerebral perfusion and neuropsychological consequences of chronic cocaine use

1993 • 271 citations

Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5

2003 • 237 citations

Cocaine-Induced Cerebral Vasoconstriction Detected in Humans With Magnetic Resonance Angiography

1998 • 207 citations

Reduced frontal white matter integrity in cocaine dependence: a controlled diffusion tensor imaging study

2002 • 192 citations

Brain perfusion is abnormal in cocaine-dependent polydrug users: a study using technetium-99m-HMPAO and ASPECT.

1991 • 163 citations

Up-regulation of D3 dopamine receptor mRNA in the nucleus accumbens of human cocaine fatalities

1997 • 159 citations

The Pathobiology of Myelin Mutants Reveal Novel Biological Functions of the MBP and PLP Genes

2001 • 133 citations

Identification of the Dopamine D3 Receptor in Oligodendrocyte Precursors: Potential Role in Regulating Differentiation and Myelin Formation

1998 • 120 citations

Gender Effects on Persistent Cerebral Metabolite Changes in the Frontal Lobes of Abstinent Cocaine Users

1999 • 120 citations

CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: Ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents

1999 • 119 citations

From neurobiology to treatment: progress against addiction

2002 • 118 citations

Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers

2002 • 105 citations

Molecular profiling of midbrain dopamine regions in cocaine overdose victims

2003 • 103 citations

White Matter Changes in the Gerbil Brain Under Chronic Cerebral Hypoperfusion

1998 • 103 citations

Human cocaine- and amphetamine-regulated transcript (CART) mRNA is highly expressed in limbic- and sensory-related brain regions

2000 • 91 citations

Human cocaine‐ and amphetamine‐regulated transcript (CART) mRNA is highly expressed in limbic‐ and sensory‐related brain regions

2000 • 91 citations

Brain maturation may be arrested in chronic cocaine addicts

2002 • 86 citations

Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse

2003 • 82 citations

Magnetic resonance imaging evidence of “silent” cerebrovascular toxicity in cocaine dependence

1999 • 82 citations

The incidence of T2-weighted MR imaging signal abnormalities in the brain of cocaine-dependent patients is age-related and region-specific.

1999 • 77 citations

Characterisation of messenger RNA extracted post-mortem from the brains of schizophrenic, depressed and control subjects.

1988 • 70 citations

Neuropsychological functioning in cocaine abusers with and without alcohol dependence

1999 • 70 citations

Repeated cocaine administration alters the expression of genes in corticolimbic circuitry after a 3‐week withdrawal: a DNA macroarray study

2002 • 66 citations

Neurochemical alterations in asymptomatic abstinent cocaine users: A proton magnetic resonance spectroscopy study

1997 • 63 citations

Large-scale analysis of gene expression changes during acute and chronic exposure to Δ9-THC in rats

2000 • 58 citations

Neurobiology of cocaine-induced organic brain impairment: contributions from functional neuroimaging.

1998 • 54 citations

Radiological and neurological changes in the drug abuse patient: a study with MRI.

1988 • 50 citations

Postnatal localization and morphogenesis of cells expressing the dopaminergic D2 receptor gene in rat brain: Expression in non-neuronal cells

1998 • 45 citations

Stability of messenger RNA in postmortem human brains and construction of human brain cDNA libraries

1990 • 43 citations

Preprotachykinin gene expression in the human basal ganglia: characterization of mRNAs and pre-mRNAs produced by alternate RNA splicing

1992 • 36 citations

Resting Hand Tremor in Abstinent Cocaine‐Dependent, Alcohol‐Dependent, and Polydrug‐Dependent Patients

1996 • 33 citations

Ultraviolet absorbance at 260 and 280 nm in RNA measurement is dependent on measurement solution.

2000 • 32 citations

Development under the influence of cocaine. II. Comparison of the effects of maternal cocaine and associated undernutrition on brain myelin development in the offspring

1990 • 30 citations

Cited By (0)

No citing papers found in database

Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for… (2004) – Journal of Neurochemistry | Metascience Observatory Explorer