Preprotachykinin gene expression in the human basal ganglia: characterization of mRNAs and pre-mRNAs produced by alternate RNA splicing

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Current protocols in molecular biology

1988 • 7,584 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Neurotransmitters and neuromodulators in the basal ganglia

1990 • 1,578 citations

High-Efficiency Cloning of Full-Length cDNA

1982 • 1,309 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1990 • 1,021 citations

Differential loss of striatal projection neurons in Huntington disease.

1988 • 976 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

High-efficiency cloning of full-length cDNA.

1982 • 763 citations

Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A.

1987 • 651 citations

Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing

1984 • 563 citations

COMPLEX TRANSCRIPTIONAL UNITS: DIVERSITY IN GENE EXPRESSION BY ALTERNATIVE RNA PROCESSING

1986 • 486 citations

Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms ¹

1990 • 449 citations

Pro- and anticonvulsant actions of morphine and the endogenous opioids: Involvement and interactions of multiple opiate and non-opiate systems

1983 • 285 citations

Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, neuropeptide K, and neuropeptide gamma

1990 • 227 citations

Extensive postmortem stability of RNA from rat and human brain

1986 • 226 citations

Substance P in the human brain

1986 • 183 citations

Dopamine antagonist haloperidol decreases substance P, substance K, and preprotachykinin mRNAs in rat striatonigral neurons.

1986 • 161 citations

mRNA in the Mammalian Central Nervous System

1988 • 153 citations

Neuropeptide K: A major tachykinin in plasma and tumor tissues from carcinoid patients

1985 • 153 citations

Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains

1983 • 148 citations

The distribution of substance P in the primate basal ganglia: An immunohistochemical study of baboon and human brain

1984 • 127 citations

Striatal tachykinin biosynthesis: regulation of mRNA and peptide levels by dopamine agonists and antagonists

1987 • 110 citations

cDNA sequence of human β‐preprotachykinin, the common precursor to substance P and neurokinin A

1986 • 95 citations

Substance P immunoreactivity in the post-mortem parkinsonian brain

1984 • 69 citations

A Sequential splicing mechanism promotes selection of an optimal exon by repositioning a downstream 5' splice site in preprotachykinin pre-mRNA.

1990 • 69 citations

Striatal tachykinin gene expression regulated by interaction of D-1 and D-2 dopamine receptors.

1989 • 61 citations

Stimulation of Pituitary Luteinizing Hormone Secretion by Gonadotropin-Releasing Hormone is Not Coupled to β-Luteinizing Hormone Gene Transcription

1988 • 56 citations

Stability of messenger RNA in postmortem human brains and construction of human brain cDNA libraries

1990 • 43 citations

Intervening sequence-specific in situ hybridization: detection of the pro-opiomelanocortin gene primary transcript in individual neurons

1989 • 38 citations

Substance P neuronal cell bodies in the human brain: Complete mapping by immunohistofluorescence

1986 • 35 citations

Preprotachykinin messenger RNA detected by in situ hybridization in striatal neurons of the human brain

1987 • 34 citations

"Snurps"

1988 • 24 citations

Expression of a Human Cocaine‐Sensitive Dopamine Transporter in Xenopus laevis Oocytes

1990 • 24 citations

Evidence for Dual Mechanisms Involved in Methamphetamine-induced Increases in Striatal Preprotachykinin mRNA

1989 • 23 citations

Substance P-like immunoreactivity in brains with pathological features of Parkinson's and Alzheimer's diseases

1989 • 23 citations

Developmental Profile of Striatal Preprotachykinin Gene Expression

1990 • 12 citations

Developmental Changes in Levels of Proopiomelanocortin Intron A-Containing Heterogeneous Nuclear RNA and Mature Messenger RNA in the Anterior and Neurointermediate Lobes of the Rat Pituitary

1990 • 12 citations