Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density.

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

1990 • 1,592 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells

1990 • 802 citations

Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

1990 • 746 citations

Interaction of chlamydiae and host cells in vitro

1991 • 734 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells

1987 • 599 citations

Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane.

1975 • 595 citations

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.

1991 • 578 citations

A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12

1985 • 535 citations

Comparative biology of intracellular parasitism

1985 • 442 citations

Discrimination Between Intracellular Uptake and Surface Adhesion of Bacterial Pathogens

1991 • 302 citations

Comparison of the invasion strategies used by Salmonella cholerae-suis, Shigella flexneri and Yersinia enterocolitica to enter cultured animal cells: endosome acidification is not required for bacterial invasion or intracellular replication

1988 • 278 citations

Cloning and expression of the gene for a fibronectin-binding protein from Staphylococcus aureus.

1987 • 255 citations

Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein.

1990 • 242 citations

Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium

1992 • 224 citations

Circulating integrins: alpha 5 beta 1, alpha 6 beta 4 and Mac-1, but not alpha 3 beta 1, alpha 4 beta 1 or LFA-1.

1992 • 218 citations

Morphological and cytoskeletal changes in epithelial cells occur immediately upon interaction with Salmonella typhimurium grown under low‐oxygen conditions

1992 • 214 citations

Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells

1983 • 197 citations

Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells

1992 • 188 citations

Integrin, A Transmembrane Glycoprotein Complex Mediating Cell-Substratum Adhesion

1987 • 176 citations

Fibronectin Binds to Some Bacteria But Does Not Promote Their Uptake by Phagocytic Cells

1983 • 137 citations

The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor.

1991 • 136 citations

cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide.

1986 • 115 citations

Genetic Determinants of Shigella Pathogenicity

1988 • 85 citations

The integrin-binding domain of invasin is sufficient to allow bacterial entry into mammalian cells

1992 • 76 citations

Microelisa reader quantitation of fixed, stained, solubilized cells in microtitre dishes.

1988 • 76 citations

Interaction of fibronectin-coated beads with attached and spread fibroblasts

1986 • 63 citations

Comparison of Chromogens for the Determination of Horseradish Peroxidase as a Marker in Enzyme Immunoassay

1981 • 62 citations

Pathways for the penetration of enteroinvasive Yersinia into mammalian cells.

1990 • 59 citations

Studies on the Pathogenicity of Yersinia enterocolitica

1977 • 45 citations

Cultured human fibroblasts contain a large pool of precursor β₁‐integrin but lack an intracellular pool of mature subunit

1991 • 42 citations

Binding and phagocytosis of fibronectin‐coated beads by BHK cells: Receptor specificity and dynamics

1985 • 29 citations

Microelisa reader quantitation of fixed, stained, solubilized cells in microtitre dishes.

1988 • 28 citations