Cultured human fibroblasts contain a large pool of precursor β₁‐integrin but lack an intracellular pool of mature subunit

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 672 citations

Regulated expression and binding of three VLA (β1) integrin receptors on T cells

1990 • 634 citations

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

1987 • 574 citations

The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.

1987 • 512 citations

Cell adhesion protein receptors as targets for transforming growth factor-$beta; action

1987 • 498 citations

Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface.

1987 • 435 citations

The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.

1989 • 388 citations

Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.

1989 • 363 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts.

1988 • 340 citations

Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium.

1988 • 333 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

Integrins and tumor cell dissemination.

1989 • 294 citations

Association of the VLA a Subunit with a Novel Protein

1989 • 285 citations

Alpha 2 beta 1 integrins from different cell types show different binding specificities.

1990 • 274 citations

Subcellular localization of the large subunit of Mo1 (Mo1 alpha; formerly gp 110), a surface glycoprotein associated with neutrophil adhesion.

1984 • 249 citations

An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2.

1987 • 246 citations

Endocytosis and recycling of the fibronectin receptor in CHO cells.

1989 • 231 citations

Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines.

1979 • 230 citations

Resting platelets contain a substantial centrally located pool of glycoprotein IIb-IIIa complex which may be accessible to some but not other extracellular proteins.

1986 • 191 citations

Modulation of vitronectin receptor binding by membrane lipid composition.

1990 • 180 citations

The interaction of fibronectin fragments with fibroblastic cells.

1985 • 168 citations

A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.

1989 • 167 citations

The cell surface glycoprotein Mac-1 (CD11b/CD18) mediates neutrophil adhesion and modulates degranulation independently of its quantitative cell surface expression.

1989 • 158 citations

Analysis of the role of glycosylation of the human fibronectin receptor

1989 • 154 citations

Internalization and cycling of the T cell antigen receptor. Role of protein kinase C.

1987 • 133 citations

An alternative cytoplasmic domain of the integrin beta 3 subunit.

1989 • 123 citations

Biosynthesis and processing of platelet GPIIb-IIIa in human megakaryocytes.

1987 • 106 citations

Biosynthesis and acquisition of biological activity of the fibronectin receptor.

1987 • 104 citations

Quantitation of intracellular membrane-bound enzymes and receptors in digitonin-permeabilized cells

1983 • 101 citations

Processing and Assembly of the Integrin, Glycoprotein IIb-IIIa, in HEL Cells

1989 • 91 citations

Comparison of fibronectin receptors from rat hepatocytes and fibroblasts.

1987 • 82 citations

Expression and function of a putative cell surface receptor for fibronectin in hamster and human cell lines.

1986 • 81 citations

Differences in the biosynthesis and localization of the fibronectin receptor in normal and transformed cultured human cells.

1990 • 73 citations

Phorbol Ester Induces Increased Expression, Altered Glycosylation, and Reduced Adhesion of K562 Erythroleukemia Cell Fibronectin Receptors

1989 • 73 citations

Distribution of the beta 1 subgroup of the integrins in human cells and tissues.

1989 • 70 citations

Internalization of the fibronectin receptor is a constitutive process

1990 • 55 citations

Kinetic and morphological evidence for endocytosis of mammalian cell integrin receptors by using an anti-fibronectin receptor β subunit monoclonal antibody

1989 • 54 citations

Matrix assembly sites for exogenous fibronectin are decreased on human fibroblasts after treatment with agents which increase intracellular cAMP.

1987 • 44 citations

Binding and phagocytosis of fibronectin‐coated beads by BHK cells: Receptor specificity and dynamics

1985 • 29 citations

Alteration of fibronectin receptors (integrins) in phorbol ester-treated human promonocytic leukemia cells.

1988 • 27 citations

Post‐translational modification of the β‐subunit of the human fibronectin receptor

1988 • 27 citations

Association between fibronectin receptor and the substratum: Spare receptors for cell adhesion

1987 • 25 citations

Evidence for the recycling nature of the fibronectin receptor of macrophages

1987 • 23 citations

Monoclonal antibody DH12 reacts with a cell surface and a precursor form of the ? subunit of the human fibronectin receptor

1988 • 21 citations

Phorbol esters and calcium ionophores inhibit internalization and accelerate recycling of receptors in macrophages.

1987 • 20 citations

Mapping of structure-function relationships in proteins with a panel of monoclonal antibodies

1988 • 16 citations

Regulation of synthesis of macrophage adhesion molecule, a heterodimeric membrane glycoprotein.

1988 • 7 citations