Molecular mechanisms of retinoid actions in skin

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Molecular basis of sun-induced premature skin ageing and retinoid antagonism

1996 • 1,379 citations

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

1995 • 1,089 citations

Nonsteroid nuclear receptors: What Are genetic studies telling us about their role in real life?

1995 • 1,011 citations

Characterization of Mechanisms Involved in Transrepression of NF-κB by Activated Glucocorticoid Receptors

1995 • 815 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.

1993 • 541 citations

Topical Tretinoin Improves Photoaged Skin

1988 • 491 citations

Restoration of Collagen Formation in Photodamaged Human Skin by Tretinoin (Retinoic Acid)

1993 • 472 citations

Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro

1974 • 437 citations

Nuclear Receptor/AP-1 Interaction*

1993 • 435 citations

Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding

1994 • 432 citations

Reduced Type I and Type III Procollagens in Photodamaged Adult Human Skin

1995 • 382 citations

Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

1995 • 361 citations

Application of Retinol to Human Skin In Vivo Induces Epidermal Hyperplasia and Cellular Retinoid Binding Proteins Characteristic of Retinoic Acid but Without Measurable Retinoic Acid Levels or Irritation

1995 • 328 citations

UVA‐INDUCED AUTOCRINE STIMULATION OF FIBROBLAST‐DERIVED COLLAGENASE/MMP‐1 BY INTERRELATED LOOPS OFINTERLEUKIN–1 andINTERLEUKIN–6

1994 • 271 citations

The nature of photoaging: its prevention and repair.

1986 • 260 citations

Retinoic Acid Receptor Gene Expression in Human Skin

1991 • 212 citations

Cellular, Immunologic and Biochemical Characterization of Topical Retinoic Acid—Treated Human Skin

1991 • 186 citations

Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin.

1994 • 179 citations

Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

1995 • 167 citations

Topical Tretinoin (Retinoic Acid) Treatment for Liver Spots Associated with Photodamage

1992 • 165 citations

Auto-regulation of Retinoic Acid Biosynthesis through Regulation of Retinol Esterification in Human Keratinocytes

1996 • 134 citations

Differential Regulation of Retinoic Acid Receptors and Binding Proteins in Human Skin

1992 • 118 citations

Biological activity of all-trans retinol requires metabolic conversion to all-trans retinoic acid and is mediated through activation of nuclear retinoid receptors in human keratinocytes

1994 • 116 citations

Topical All-Trans Retinoic Acid Stimulates Collagen Synthesis In Vivo

1990 • 114 citations

Negative transcriptional regulation by nuclear receptors.

1994 • 106 citations

Cloning of a cDNA for a Second Retinol Dehydrogenase Type II

1995 • 99 citations

Retinoic acid induction of human cellular retinoic acid-binding protein-II gene transcription is mediated by retinoic acid receptor-retinoid X receptor heterodimers bound to one far upstream retinoic acid-responsive element with 5-base pair spacing.

1994 • 91 citations

Endogenous Retinoic Acid Receptor (RAR)-Retinoid X Receptor (RXR) Heterodimers Are the Major Functional Forms Regulating Retinoid-responsive Elements in Adult Human Keratinocytes

1995 • 90 citations

A retinoic acid response element from the rat CRBPI promoter is activated by an RARRXR heterodimer

1992 • 86 citations

Glandular metaplasia of hair follicles and other responses to vitamin A excess in cultures of rodent skin

1968 • 77 citations

Extraction of Human Epidermis Treated with Retinol Yields Retro-Retinoids in Addition to Free Retinol and Retinyl Esters

1996 • 76 citations

Retinoic Acid Receptor Gamma Mediates Topical Retinoid Efficacy and Irritation in Animal Models

1995 • 65 citations

Filaggrin production by cultured human epidermal keratinocytes and its regulation by retinoic acid

1990 • 58 citations

Retinoic Acid Isomers Applied to Human Skin in Vivo Each Induce a 4-Hydroxylase That Inactivates Only Trans Retinoic Acid

1996 • 58 citations

Changes in Photo-Aged Human Skin Following Topical Application of All-Trans Retinoic Acid

1990 • 56 citations

Expression of loricrin is negatively controlled by retinoic acid in human epidermis reconstructed in vitro

1992 • 52 citations

Retinoic acid metabolites exhibit biological activity in human keratinocytes, mouse melanoma cells and hairless mouse skin in vivo.

1993 • 43 citations

Retinoids and the Skin

2009 • 40 citations

A Pleiotropic Response Is Induced in F9 Embryonal Carcinoma Cells and Rhino Mouse Skin by All-trans-Retinoic Acid, a RAR Agonist but Not by SR11237, a RXR-Selective Agonist

1994 • 29 citations

Characterization of Human Cellular Retinoic Acid-Binding Protein-I and Protein-II: Ligand-Binding Affinities and Distribution in Skin

1994 • 25 citations

Characterization and purification of human retinoic acid receptor-γ 1 overexpressed in the baculovirus-insect cell system

1992 • 15 citations