Virus-specific memory and effector T lymphocytes exhibit different cytokine responses to antigens during experimental murine respiratory syncytial virus infection

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

RESPIRATORY SYNCYTIAL VIRUS DISEASE IN INFANTS DESPITE PRIOR ADMINISTRATION OF ANTIGENIC INACTIVATED VACCINE12

1969 • 1,921 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production.

1991 • 705 citations

FIELD EVALUATION OF A RESPIRATORY SYNCYTIAL VIRUS VACCINE AND A TRIVALENT PARAINFLUENZA VIRUS VACCINE IN A PEDIATRIC POPULATION1

1969 • 612 citations

IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis.

1991 • 526 citations

Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice.

1991 • 499 citations

In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific.

1984 • 439 citations

Differentiation of T cell lymphokine gene expression: the in vitro acquisition of T cell memory.

1991 • 406 citations

Primary respiratory syncytial virus infection in mice

1988 • 381 citations

Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major.

1989 • 374 citations

Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10

1994 • 352 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.

1989 • 349 citations

Distinct types of lung disease caused by functional subsets of antiviral T cells.

1994 • 318 citations

Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells.

1993 • 313 citations

Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection.

1994 • 283 citations

Pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of CD4+ T cells

1992 • 270 citations

AN ANTIGENIC ANALYSIS OF RESPIRATORY SYNCYTIAL VIRUS ISOLATES BY A PLAQUE REDUCTION NEUTRALIZATION TEST1

1966 • 237 citations

Pulmonary eosinophilic response to respiratory syncytial virus infection in mice sensitized to the major surface glycoprotein G

1992 • 228 citations

From the National Institute of Allergy and Infectious Diseases and the World Health Organization: Respiratory Syncytial and Parainfluenza Viruses

1990 • 222 citations

Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus

1987 • 215 citations

Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor.

1992 • 165 citations

Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus.

1994 • 145 citations

Characterization of murine lung dendritic cells: similarities to Langerhans cells and thymic dendritic cells.

1990 • 134 citations

Expression of the fusion protein of human respiratory syncytial virus from recombinant vaccinia virus vectors and protection of vaccinated mice

1987 • 132 citations

Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins.

1993 • 129 citations

In vivo blockade of gamma interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue

1996 • 126 citations

Novel features of the respiratory tract T-cell response to influenza virus infection: lung T cells increase expression of gamma interferon mRNA in vivo and maintain high levels of mRNA expression for interleukin-5 (IL-5) and IL-10

1994 • 99 citations

Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen.

1993 • 97 citations

Distinct patterns of T- and B-cell immunity to respiratory syncytial virus induced by individual viral proteins

1993 • 86 citations

Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype.

1994 • 86 citations

IL-4- and IL-5-secreting lymphocyte populations are preferentially stimulated by parasite-derived antigens in human tissue invasive nematode infections.

1993 • 83 citations

Expression of the major glycoprotein G of human respiratory syncytial virus from recombinant vaccinia virus vectors.

1986 • 73 citations

Cytokine Response To Respiratory Syncytial Virus Stimulation Of Human

1994 • 72 citations

Induction of cytokines in mice with parainfluenza pneumonia

1995 • 68 citations

Expansion/deletion of mature T cells exposed to endogenous superantigens in vivo.

1994 • 56 citations