In vivo isomerization of retinoic acids. Rapid isomer exchange and gene expression.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

Function of retinoic acid receptor γ in the mouse

1993 • 595 citations

Two nuclear signalling pathways for vitamin D

1993 • 559 citations

Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1991 • 527 citations

Retinoic Acid Receptors and Cellular Retinoid Binding Proteins: Complex Interplay in Retinoid Signaling*

1994 • 514 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse

1989 • 482 citations

All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs

1992 • 417 citations

The nucleotide sequence of the chick cytoplasmic β-actin gene

1983 • 336 citations

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR.

1993 • 307 citations

Polarizing activity and retinoid synthesis in the floor plate of the neural tube

1990 • 292 citations

A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically

1992 • 290 citations

Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.

1993 • 272 citations

Isolation of 3,4-didehydroretinoic acid, a novel morphogenetic signal in the chick wing bud

1990 • 252 citations

The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells.

1992 • 237 citations

Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors.

1993 • 207 citations

Intracellular Signaling by 14-hydroxy-4,14- Retro -Retinol

1991 • 184 citations

The cellular retinol binding protein II gene. Sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene.

1987 • 126 citations

13-cis-retinoic acid is an endogenous compound in human serum.

1990 • 108 citations

Effect of retinoid status on α, β and γ retinoic acid receptor mRNA levels in various rat tissues

1992 • 105 citations

Regulation of Hepatic Lecithin: Retinol Acyltransferase Activity by Retinoic Acid

1993 • 76 citations

Metabolism of all-trans-retinoic acid and all-trans-retinyl acetate. Demonstration of common physiological metabolites in rat small intestinal mucosa and circulation.

1985 • 76 citations

Divergent effects of 9-cis-retinoic acid receptor on positive and negative thyroid hormone receptor-dependent gene expression.

1993 • 61 citations

Positive and negative regulation of retinoid X receptor gene expression by thyroid hormone in the rat. Transcriptional and post-transcriptional controls by thyroid hormone.

1994 • 53 citations

Retinobenzoic Acids and Nuclear Retinoic Acid Receptors.

1991 • 47 citations

Enhancement of Biological Activity by Conjugation Reactions

1992 • 45 citations

Rat cellular retinol-binding protein: cDNA sequence and rapid retinol-dependent accumulation of mRNA.

1987 • 41 citations

Thyroid Hormone Affects the Gene Expression of Retinoid X Receptors in the Adult Rat

1993 • 37 citations

Induction of HL‐60 cell differentiation by water‐soluble and nitrogen‐containing conjugates of retinoic acid and retinol

1991 • 37 citations

Metabolism in vivo of all-trans-[11-3H]retinoic acid after an oral dose in rats. Characterization of retinoyl β-glucuronide in the blood and other tissues

1991 • 23 citations

Tissue-specific response of estrogen receptor gene expression to estrogen in chick

1992 • 16 citations

Gene Expression of Cellular Retinol-Binding Protein I (CRBP I) is Affected by Dietary Proteins in the Rat Liver.

1993 • 8 citations

Cellular Retinol-Binding Protein Functions in the Regulation of Retinoid Metabolism

2009 • 3 citations