DnaK, DnaJ and GrpE form a cellular chaperone machinery capable of repairing heat-induced protein damage.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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1987 • 3,088 citations

Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu

1976 • 1,895 citations

MOLECULAR CHAPERONES

1991 • 1,089 citations

Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding

1992 • 965 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate

1991 • 853 citations

Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK.

1991 • 835 citations

Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 • 763 citations

GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli

1989 • 703 citations

Is hsp70 the cellular thermometer?

1991 • 586 citations

Ribosomes as sensors of heat and cold shock in Escherichia coli.

1990 • 516 citations

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

1990 • 407 citations

Chaperonin-facilitated refolding of ribulose bisphosphate carboxylase and ATP hydrolysis by chaperonin 60 (groEL) are potassium dependent

1990 • 384 citations

DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.

1990 • 356 citations

Regulation of the Escherichia coli heat‐shock response

1993 • 338 citations

The dnaK protein modulates the heat-shock response of Escherichia coli

1983 • 328 citations

Physical interaction between heat shock proteins DnaK, DnaJ, and GrpE and the bacterial heat shock transcription factor σ32

1992 • 314 citations

Protein Folding in the Cell: The Role of Molecular Chaperones Hsp70 and Hsp60

1992 • 306 citations

THE UNIVERSALLY CONSERVED GroE (Hsp60) CHAPERONINS

1991 • 293 citations

Transcription from efficient promoters can interfere with plasmid replication and diminish expression of plasmid specified genes.

1982 • 281 citations

Regulation of Hsp70 function by a eukaryotic DnaJ homolog.

1992 • 262 citations

Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation.

1992 • 239 citations

Cellular defects caused by deletion of the Escherichia coli dnaK gene indicate roles for heat shock protein in normal metabolism

1989 • 234 citations

DnaK as a thermometer: threonine-199 is site of autophosphorylation and is critical for ATPase activity.

1991 • 218 citations

Escherichia coli heat shock gene mutants are defective in proteolysis.

1988 • 205 citations

Involvement of the chaperonin dnaK in the rapid degradation of a mutant protein in Escherichia coli.

1992 • 199 citations

The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor.

1992 • 178 citations

Protein Denaturation during Heat Shock and Related Stress

1989 • 166 citations

Stress proteins in biology and medicine

1991 • 154 citations

Mutations altering heat shock specific subunit of RNA polymerase suppress major cellular defects of E. coli mutants lacking the DnaK chaperone.

1990 • 146 citations

Renaturation of denatured λ repressor requires heat shock proteins

1990 • 123 citations

Delta dnaK52 mutants of Escherichia coli have defects in chromosome segregation and plasmid maintenance at normal growth temperatures

1989 • 117 citations

Organization and expression of the dnaJ and dnaK genes of Escherichia coli K12

1978 • 110 citations

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

1988 • 106 citations

Genetic engineering. Principles and methods

1987 • 105 citations

The heat-shock-regulated grpE gene of Escherichia coli is required for bacterial growth at all temperatures but is dispensable in certain mutant backgrounds

1989 • 104 citations

Three Escherichia coli heat shock proteins are required for P1 plasmid DNA replication: formation of an active complex between E. coli DnaJ protein and the P1 initiator protein.

1990 • 100 citations

A new host gene (groPC) necessary for lambda DNA replication

1977 • 94 citations

A module of the DnaJ heat shock proteins found in malaria parasites

1992 • 93 citations

Isolation and characterization of a temperature-sensitive dnaK mutant of Escherichia coli B

1979 • 87 citations

Denaturation of proteins during heat shock. In vivo recovery of solubility and activity of reporter enzymes

1991 • 82 citations

Physical interactions between bacteriophage and Escherichia coli proteins required for initiation of lambda DNA replication.

1990 • 75 citations

Interaction between heat shock protein DnaK and recombinant staphylococcal protein A

1990 • 42 citations

Purification of Complexes of Nuclear Oncogene p53 with Rat and Escherichia coli Heat Shock Proteins: In Vitro Dissociation of hsc70 and dnaK from Murine p53 by ATP

1988 • 28 citations

Antibody to sigma 32 cross-reacts with DnaK: association of DnaK protein with Escherichia coli RNA polymerase.

1988 • 23 citations

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