Soluble Fas in serum from patients with renal cell carcinoma

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Prognostic significance of morphologic parameters in renal cell carcinoma

1982 • 2,700 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

1995 • 1,212 citations

Protection from Fas-Mediated Apoptosis by a Soluble Form of the Fas Molecule

1994 • 1,120 citations

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.

1992 • 857 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

1993 • 643 citations

International Union Against Cancer (UICC)

2012 • 472 citations

DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement

1992 • 392 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

Fas and Fas Ligand: A Death Factor and Its Receptor

1994 • 354 citations

Anti-Fas on nonhematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness.

1994 • 262 citations

Resistance to Fas-mediated apoptosis in human hepatoma cells.

1995 • 152 citations

Identification of soluble APO-1 in supernatants of human B- and T-cell lines and increased serum levels in B- and T-cell leukemias

1995 • 148 citations

Elevated soluble Fas (sFas) levels in nonhematopoietic human malignancy.

1996 • 142 citations

Fas/APO-1 gene transfer for human malignant glioma.

1995 • 127 citations

Soluble Fas/APO-1 in tumor cells: a potential regulator of apoptosis?

1995 • 110 citations

PROGNOSTIC SIGNIFICANCE OF SOLUBLE FAS IN THE SERUM OF PATIENTS WITH BLADDER CANCER

1998 • 89 citations

Characterization of an established cell line from human renal carcinoma.

1979 • 29 citations

Tetrapeptide DEVD-aldehyde or YVAD-chloromethylketone inhibits Fas/Apo-1 (CD95)-mediated apoptosis in renal-cell-cancer cells

1996 • 26 citations

Fas/APO-1-Mediated Apoptosis of Human Renal Cell Carcinoma

1996 • 26 citations