Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Biological and clinical aspects of interleukin 6

1990 • 1,091 citations

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1990 • 753 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Growth factors in development, transformation, and tumorigenesis

1991 • 695 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

IgG1 plasmacytosis in interleukin 6 transgenic mice.

1989 • 597 citations

Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice

1990 • 447 citations

A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro

1986 • 391 citations

Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

1987 • 384 citations

Induction of Plasma-Cell Neoplasms in Strain BALB/c Mice with Mineral Oil and Mineral Oil Adjuvants

1962 • 311 citations

Establishment of an interleukin 6 (IL 6)/B cell stimulatory factor 2‐dependent cell line and preparation of anti‐IL 6 monoclonal antibodies

1988 • 308 citations

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6

1988 • 292 citations

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus

1984 • 274 citations

Nonrandom chromosome changes involving the Ig gene-carrying chromosomes 12 and 6 in pristane-induced mouse plasmacytomas

1979 • 209 citations

Negative regulation of the major histocompatibility class I gene in undifferentiated embryonal carcinoma cells.

1986 • 123 citations

Growth factors as transforming proteins

1989 • 122 citations

Chromosomal translocations activating myc sequences and transduction of v-abl are critical events in the rapid induction of plasmacytomas by pristane and abelson virus.

1984 • 106 citations

An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.

1990 • 84 citations

The assignment of chain specificities for anti-Ia monoclonal antibodies using L cell transfectants.

1986 • 83 citations

Avian v-mycReplaces Chromosomal Translocation in Murine Plasmacytomagenesis

1987 • 65 citations

Introduction of Human γ1 Immunoglobulin Genes into Fertilized Mouse Eggs1

1984 • 50 citations