Acute leukaemia in bcr/abl transgenic mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 • 1,385 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

1988 • 741 citations

Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

1983 • 699 citations

Surface Antigen Expression and Immunoglobulin Gene Rearrangement During Mouse pre‐B Cell Development

1983 • 490 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

1987 • 405 citations

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia

1986 • 186 citations

Clinical and biologic hallmarks of the Philadelphia chromosome in childhood acute lymphoblastic leukemia

1987 • 173 citations

Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.

1986 • 160 citations

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.

1989 • 145 citations

A bcr-v-abl oncogene induces lymphomas in transgenic mice.

1989 • 125 citations

Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes.

1986 • 124 citations

Relationships between B cell and myeloid differentiation. Studies with a B lymphocyte progenitor line, HAFTL-1.

1988 • 111 citations

Philadelphia chromosome positive childhood acute lymphoblastic leukemia

1980 • 102 citations

The first BCR gene intron contains breakpoints in Philadelphla chromosome positive leukemia

1988 • 55 citations

The bcr gene in Philadelphia chromosome positive acute lymphoblastic leukemia

1989 • 36 citations

Chromosomes and causation of human cancer and leukemia. XLII. Ph1-positive ALL: An entity within myeloproliferative disorders?

1980 • 34 citations

The bcr gene in Philadelphia chromosome positive acute lymphoblastic leukemia

1989 • 32 citations

Differentiation In Vitro of a Leukemia Virus-Induced B-Cell Lymphoma into Macrophages

1989 • 26 citations

Acute Lymphoblastic Leukemia

1989 • 26 citations

Differentiation in vitro of a leukemia virus-induced B-cell lymphoma into macrophages.

1989 • 21 citations