Genetic analysis of a plasmid-encoded, host genotype-specific enhancement of bacterial fitness

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

The Crisis in Antibiotic Resistance

1992 • 2,815 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations

1991 • 1,598 citations

Epidemiology of Drug Resistance: Implications for a Post—Antimicrobial Era

1992 • 1,325 citations

Positive selection for loss of tetracycline resistance

1980 • 704 citations

Selection for loss of tetracycline resistance by Escherichia coli

1981 • 585 citations

Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.

1980 • 584 citations

Resource-Limited Growth, Competition, and Predation: A Model and Experimental Studies with Bacteria and Bacteriophage

1977 • 493 citations

Constraints on the Coevolution of Bacteria and Virulent Phage: A Model, Some Experiments, and Predictions for Natural Communities

1985 • 450 citations

Evolution of a bacteria/plasmid association

1988 • 450 citations

The nucleotide sequence of pACYC184

1988 • 407 citations

Infectious multiple drug resistance.

1975 • 345 citations

Selection in chemostats

1983 • 323 citations

A Complex Community in a Simple Habitat: An Experimental Study with Bacteria and Phage

1977 • 297 citations

Revised sequence of the tetracycline-resistance gene of pBR322

1983 • 287 citations

EXPERIMENTAL STUDIES OF PLEIOTROPY AND EPISTASIS INESCHERICHIA COLI. I. VARIATION IN COMPETITIVE FITNESS AMONG MUTANTS RESISTANT TO VIRUS T4

1988 • 271 citations

Heterogeneity of tetracycline resistance determinants

1980 • 249 citations

EVOLUTIONARY ADAPTATION TO TEMPERATURE. I. FITNESS RESPONSES OF ESCHERICHIA COLI TO CHANGES IN ITS THERMAL ENVIRONMENT

1992 • 246 citations

Effects of recombinant plasmid content on growth properties and cloned gene product formation in Escherichia coli

1985 • 242 citations

A bacterial virulence determinant encoded by lysogenic coliphage λ

1990 • 190 citations

The Influence of the Growth Environment on the Stability of a Drug Resistance Plasmid in Escherichia coli K12

1979 • 189 citations

Revised Interpretation of the Origin of the pSC101 Plasmid

1977 • 188 citations

Kinetic study of instability of recombinant plasmid pPLc23trpAl in E. coli using two‐stage continuous culture system

1985 • 185 citations

The effect of genetic background on the fitness of diazinon resistance genotypes of the Australian sheep blowfly, Lucilia cuprina

1982 • 178 citations

EXPERIMENTAL STUDIES OF PLEIOTROPY AND EPISTASIS INESCHERICHIA COLI. II. COMPENSATION FOR MALADAPTIVE EFFECTS ASSOCIATED WITH RESISTANCE TO VIRUS T4

1988 • 174 citations

The Maintenance of Plasmid-containing Organisms in Populations of Escherichia coli

1981 • 163 citations

Effects of carriage and expression of the Tn10 tetracycline-resistance operon on the fitness of Escherichia coli K12.

1989 • 150 citations

Experimental Studies of Pleiotropy and Epistasis in Escherichia coli. I. Variation in Competitive Fitness Among Mutants Resistant to Virus T4

1988 • 144 citations

Maintenance and genetic stability of vector plasmids pBR322 and pBR325 in Escherichia coli K12 strains grown in a chemostat

1981 • 141 citations

A new revision of the sequence of plasmid pBR322

1988 • 141 citations

Generation time-prolonging R plasmids: Correlation between increases in the generation time of Escherichia coli caused by R plasmids and their molecular size

1980 • 132 citations

Maintenance of some ColE1-type plasmids in chemostat culture

1980 • 126 citations

Quantifying Fitness and Gene Stability in Microorganisms

1991 • 121 citations

Overproduction of transposon Tn10-encoded tetracycline resistance protein results in cell death and loss of membrane potential

1989 • 107 citations

COEVOLUTION IN BACTERIAL-PLASMID POPULATIONS

1991 • 105 citations

Transposable element IS50 improves growth rate of E. coli cells without transposition

1983 • 105 citations

λ Lysogens of E. coli reproduce more rapidly than non-lysogens

1975 • 104 citations

Expression of tetracycline resistance in pBR322 derivatives reduces the reproductive fitness of plasmid-containing Escherichia coli

1985 • 96 citations

Effects of segregation and selection on instability of plasmid pACYC184 in Escherichia coli B

1987 • 92 citations

Persistence of tetracycline resistance in pig E. coli

1975 • 88 citations

Increased reproductive fitness of Escherichia coli lambda lysogens

1977 • 82 citations

EVOLUTION OF TRANSPOSONS: NATURAL SELECTION FOR Tn5 IN ESCHERICHIA COLI K12

1983 • 76 citations

Multicopy Tn10 tet plasmids confer sensitivity to induction of tet gene expression

1983 • 72 citations

A Mathematical Method for Analysing Plasmid Stability in Micro-organisms

1987 • 72 citations

Tetracycline resistance element of pBR322 mediates potassium transport

1984 • 49 citations

Plasmid macro-evolution: selection of deletions during adaptation in a nutrient-limited environment

1991 • 49 citations

Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression

1983 • 43 citations

The insertion of large pieces of foreign genetic material reduces the stability of bacterial plasmids

1986 • 42 citations

Antibiotic Resistance Genes: Ecology, Transfer, and Expression

1987 • 37 citations

Bleomycin-resistance gene derived from the transposon Tn5 confers selective advantage to Escherichia coli K-12.

1991 • 36 citations

The ecology and evolution of tetracycline resistance

1992 • 33 citations

A Bacteriophage λ Cohesive Ends (cos) DNA Fragment Enhances the Fitness of Plasmid-Containing Bacteria Growing in Energy-Limited Chemostats

1984 • 33 citations

Stability of recombinant DNA and its effects on fitness

1988 • 33 citations

Plasmid-conferred tetracycline resistance confers collateral cadmium sensitivity to E. coli cells

1982 • 25 citations

Conditions for the Existence of R-Plasmids in Bacterial Populations

1980 • 24 citations

Plasmid burden in chemostat culture of Escherichia coli: Its effect on the selection for overproducers of host enzymes

1993 • 24 citations

The influences of a lambda prophage on the growth rate of Escherichia coli.

1978 • 22 citations

BsiY I, a novel thermophilic restriction endonuclease that recognizes 5′ CCNNNNNNNGG 3′ and the discovery of a wrongly sequenced site in pACYC177

1991 • 12 citations

In vivoevents in the generation of_pBR322

1986 • 2 citations