Multicopy Tn10 tet plasmids confer sensitivity to induction of tet gene expression

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Positive selection for loss of tetracycline resistance

1980 • 704 citations

MINIATURE escherichia coli CELLS DEFICIENT IN DNA

1967 • 629 citations

Selection for loss of tetracycline resistance by Escherichia coli

1981 • 585 citations

Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.

1980 • 584 citations

Functional expression of cloned yeast DNA in Escherichia coli: Specific complementation of argininosuccinate lyase (argH) mutations

1978 • 258 citations

Replication control in a composite plasmid constructed by in vitro linkage of two distinct replicons

1976 • 246 citations

A simple method for stabilizing protein-sulfhydryl groups during SDS-gel electrophoresis

1978 • 231 citations

Synthesis of Ribonucleic Acid and Protein in Plasmid-Containing Minicells of Escherichia coli K-12

1971 • 182 citations

Detection of an inducible membrane protein associated with R-factor-mediated tetracycline resistance

1974 • 143 citations

A multifunctional gene (tetR) controls Tn10-encoded tetracycline resistance

1982 • 136 citations

Overlapping divergent promoters control expression of Tn10 tetracycline resistance

1983 • 135 citations

Organization of structural and regulatory genes that mediate tetracycline resistance in transposon Tn10

1979 • 120 citations

Resistance of Escherichia coli to tetracyclines. Changes in permeability to tetracyclines in Escherichia coli bearing transferable resistance factors

1967 • 113 citations

Plasmid-mediated tetracycline resistance in escherichia coli involves increased efflux of the antibiotic

1980 • 113 citations

Specificity and Mechanism of Tetracycline Resistance in a Multiple Drug Resistant Strain of Escherichia coli

1966 • 98 citations

Synthesis of an R plasmid protein associated with tetracycline resistance is negatively regulated.

1976 • 90 citations

Two complementation groups mediate tetracycline resistance determined by Tn10

1982 • 88 citations

Plasmid-determined tetracycline resistance involves new transport systems for tetracycline

1978 • 87 citations

Identification of the tetracycline resistance promoter and repressor in transposon Tn10

1981 • 84 citations

Restriction enzyme cleavage map of Tn10, a transposon which encodes tetracycline resistance

1979 • 74 citations

Translocation of the tetracycline resistance determinant from R100-1 to the Escherichia coli K-12 chromosome

1975 • 71 citations

Analysis of the reduction in expression of tetracycline resistance determined by transposon Tn10 in the multicopy state

1981 • 62 citations

Generation of miniplasmids from copy number mutants of the R plasmid NR1

1977 • 45 citations

Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression

1983 • 43 citations

Tetracycline resistance transposon Tn1721: recA-dependent gene amplification and expression of tetracycline resistance

1981 • 35 citations

Evidence for More Than One Mechanism of Plasmid-determined Tetracycline Resistance in Escherichia coli

1980 • 33 citations

Reduced Expression of Tn10-mediated Tetracycline Resistance in Escherichia coli Containing More Than One Copy of the Transposon

1981 • 32 citations

Action of 12 Tetracyclines on Susceptible and Resistant Strains of Staphylococcus aureus

1973 • 15 citations