Global Regulation of Mitochondrial Biogenesis in Saccharomyces cerevisiae

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Biogenesis of Mitochondria

1988 • 1,396 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

The molecular biology of the yeast saccharomyces: Metabolism and gene expression

1983 • 1,118 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

The Molecular Biology of the Yeast Saccharomyces (Metabolism and Gene Expression)

1985 • 712 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

A Yeast Gene That Is Essential for Release from Glucose Repression Encodes a Protein Kinase

1986 • 688 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

DNA recognition by GAL4: structure of a protein-DNA complex

1992 • 664 citations

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

1990 • 656 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.

1980 • 567 citations

Similarity of Human Mitochondrial Transcription Factor 1 to High Mobility Group Proteins

1991 • 538 citations

Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.

1988 • 511 citations

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

1990 • 507 citations

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

1984 • 501 citations

The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein

1989 • 491 citations

Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.

1990 • 488 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Biosynthesis of heme and chlorophylls

1990 • 465 citations

A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast

1983 • 462 citations

Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer.

1989 • 432 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.

1990 • 404 citations

Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response.

1991 • 400 citations

A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

1985 • 368 citations

Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae.

1991 • 359 citations

MUTATIONS AFFECTING TY-MEDIATED EXPRESSION OF THE HIS4 GENE OF SACCHAROMYCES CEREVISIAE

1984 • 355 citations

Histone Function in Transcription

1990 • 354 citations

Glucose repression in the yeast Saccharomyces cerevisiae

1992 • 347 citations

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy

1990 • 340 citations

A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation

1987 • 332 citations

Yeast histone H4 N-terminal sequence is required for promoter activation in vivo

1991 • 330 citations

A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria.

1991 • 325 citations

Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein

1988 • 325 citations

Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

1987 • 324 citations

DNA wrapping and bending by a mitochondrial high mobility group-like transcriptional activator protein.

1992 • 322 citations

The Mitochondrial Genotype Can Influence Nuclear Gene Expression in Yeast

1987 • 318 citations

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1987 • 317 citations

Functional dissection and sequence of yeast HAP1 activator

1989 • 309 citations

Snap helix with knob and hole: Essential repeats in S. pombe nuclear protein nuc2 +

1990 • 306 citations

Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.

1986 • 295 citations

Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner

1987 • 255 citations

Multiple Global Regulators Control HIS4 transcription in Yeast

1987 • 246 citations

Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 gene

1987 • 245 citations

Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation.

1991 • 244 citations

Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein.

1989 • 236 citations

Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer.

1988 • 234 citations

A yeast protein that influences the chromatin structure of UASG and functions as a powerful auxiliary gene activator.

1990 • 229 citations

A SUPPRESSOR OF snf1 MUTATIONS CAUSES CONSTITUTIVE HIGH-LEVEL INVERTASE SYNTHESIS IN YEAST

1984 • 228 citations

Yeast promoters: Positive and negative elements

1984 • 227 citations

Signal Transduction During Pheromone Response in Yeast

1991 • 225 citations

Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Saccharomyces cerevisiae.

1991 • 220 citations

Bent DNA at a yeast autonomously replicating sequence

1986 • 217 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

Nucleo‐mitochondrial interactions in yeast mitochondrial biogenesis

1989 • 216 citations

Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae.

1990 • 207 citations

A third ADP/ATP translocator gene in yeast.

1990 • 205 citations

Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated.

1987 • 198 citations

Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: evidence for physical association of the SNF4 protein with the SNF1 protein kinase.

1989 • 197 citations

Transcriptional Regulation in the Yeast Life Cycle

1987 • 196 citations

Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae.

1987 • 192 citations

The mitochondrial respiratory chain of yeast. Structure and biosynthesis and the role in cellular metabolism

1987 • 192 citations

The HAP2 subunit of yeast CCAAT transcriptional activator contains adjacent domains for subunit association and DNA recognition: model for the HAP2/3/4 complex.

1990 • 191 citations

CPF1, a yeast protein which functions in centromeres and promoters.

1990 • 189 citations

Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning.

1987 • 185 citations

Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae.

1991 • 181 citations

Similarity Between the Transcriptional Silencer Binding Proteins ABF1 and RAP1

1989 • 180 citations

Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae.

1990 • 178 citations

Communication Between Mitochondria and the Nucleus in Regulation of Cytochrome Genes in the Yeast Saccharomyces cerevisiae

1989 • 178 citations

A positive regulatory gene is required for accumulation of the functional messenger RNA for the glucose-repressible alcohol dehydrogenase from Saccharomyces cerevisiae

1981 • 176 citations

DNA binding properties of an HMG1-related protein from yeast mitochondria.

1992 • 175 citations

Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.

1988 • 174 citations

Fermentable sugars and intracellular acidification as specific activators of the RAS‐adenylate cyclase signalling pathway in yeast: the relationship to nutrient‐induced cell cycle control

1991 • 173 citations

An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family.

1992 • 173 citations

Regulation of sugar utilization in Saccharomyces species

1987 • 172 citations

Temperature-sensitive yeast mutants defective in mitochondrial inheritance.

1990 • 169 citations

Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway.

1991 • 168 citations

A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae.

1992 • 168 citations

Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1.

1990 • 165 citations

GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats.

1991 • 165 citations

Mutations in yeast HAP2/HAP3 define a hybrid CCAAT box binding domain.

1993 • 163 citations

Assembly of the mitochondrial membrane system. Analysis of structural mutants of the yeast coenzyme QH2-cytochrome c reductase complex.

1988 • 160 citations

Isolation of a Saccharomyces cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor.

1987 • 158 citations

Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA element.

1985 • 157 citations

MET4, a leucine zipper protein, and centromere-binding factor 1 are both required for transcriptional activation of sulfur metabolism in Saccharomyces cerevisiae.

1992 • 156 citations

Evolutionary variation of the CCAAT-binding transcription factor NF-Y

1992 • 151 citations

GAL11P: A yeast mutation that potentiates the effect of weak GAL4-derived activators

1990 • 149 citations

Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.

1988 • 148 citations

RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.

1991 • 147 citations

A yeast ARS-binding protein activates transcription synergistically in combination with other weak activating factors.

1990 • 146 citations

Yeast HAP2 and HAP3: Transcriptional Activators in a Heteromeric Complex

1988 • 145 citations

The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes.

1990 • 144 citations

Sequence and nuclear localization of the Saccharomyces cerevisiae HAP2 protein, a transcriptional activator.

1987 • 143 citations

Specificity of unsaturated fatty acid-regulated expression of the Saccharomyces cerevisiae OLE1 gene.

1992 • 142 citations

Cloning and molecular analysis of the HAP2 locus: a global regulator of respiratory genes in Saccharomyces cerevisiae.

1985 • 140 citations

GENES AFFECTING THE EXPRESSION OF CYTOCHROME c IN YEAST: GENETIC MAPPING AND GENETIC INTERACTIONS

1980 • 137 citations

Heat shock response of Saccharomyces cerevisiae mutants altered in cyclic AMP-dependent protein phosphorylation.

1987 • 135 citations

Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site.

1988 • 133 citations

CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast

1988 • 128 citations

Nuclear respiratory factor 1 activation sites in genes encoding the gamma-subunit of ATP synthase, eukaryotic initiation factor 2 alpha, and tyrosine aminotransferase. Specific interaction of purified NRF-1 with multiple target genes.

1992 • 126 citations

The N-terminal TPR region is the functional domain of SSN6, a nuclear phosphoprotein of Saccharomyces cerevisiae.

1990 • 124 citations

Molecular analysis of SNF2 and SNF5, genes required for expression of glucose-repressible genes in Saccharomyces cerevisiae.

1986 • 123 citations

ROX1 encodes a heme-induced repression factor regulating ANB1 and CYC7 of Saccharomyces cerevisiae.

1988 • 121 citations

The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts.

1988 • 119 citations

Oxygen regulation of anaerobic and aerobic genes mediated by a common factor in yeast.

1984 • 119 citations

A cis-acting element present in multiple genes serves as a repressor protein binding site for the yeast CAR1 gene.

1990 • 116 citations

Isolation and characterization of the positive regulatory gene ADR1 from Saccharomyces cerevisiae.

1983 • 114 citations

Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase.

1989 • 113 citations

Yeast has a true stringent response

1978 • 113 citations

Effects of null mutations in the hexokinase genes of Saccharomyces cerevisiae on catabolite repression.

1986 • 112 citations

MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae.

1989 • 111 citations

The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae.

1990 • 110 citations

The gene encoding ARS-binding factor I is essential for the viability of yeast.

1989 • 105 citations

Two nonidentical forms of subunit V are functional in yeast cytochrome c oxidase.

1985 • 104 citations

Identification of two factors which bind to the upstream sequences of a number of nuclear genes coding for mitochondrial proteins and to genetic elements important for cell division in yeast

1988 • 103 citations

HAP1 and ROX1 Form a Regulatory Pathway in the Repression of HEM13 Transcription in Saccharomyces cerevisiae

1992 • 100 citations

Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes.

1988 • 99 citations

A role for unsaturated fatty acids in mitochondrial movement and inheritance.

1991 • 98 citations

The SNF2, SNF5 and SNF6 genes are required for Ty transcription in Saccharomyces cerevisiae.

1991 • 97 citations

Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases.

1988 • 94 citations

Nuclear and mitochondrial inheritance in yeast depends on novel cytoplasmic structures defined by the MDM1 protein.

1992 • 94 citations

Sequence, expression and mutational analysis of BAF1, a transcriptional activator and ARS1-binding protein of the yeast Saccharomyces cerevisiae.

1989 • 93 citations

Biosynthesis of the ubiquinol-cytochrome c reductase complex in yeast. Discoordinate synthesis of the 11-kd subunit in response to increased gene copy number.

1983 • 92 citations

Inverse regulation of the yeast COX5 genes by oxygen and heme.

1989 • 92 citations

Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex.

1994 • 91 citations

Positive and negative transcriptional control by heme of genes encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae.

1989 • 90 citations

Product of Saccharomyces cerevisiae nuclear gene PET494 activates translation of a specific mitochondrial mRNA.

1986 • 89 citations

Yeast Gal11 protein mediates the transcriptional activation signal of two different transacting factors, Gal4 and general regulatory factor I/repressor/activator site binding protein 1/translation upstream factor.

1990 • 88 citations

The isoforms of yeast cytochrome c oxidase subunit V alter the in vivo kinetic properties of the holoenzyme

1991 • 88 citations

Cloning and characterization of the CYC8 gene mediating glucose repression in yeast

1988 • 87 citations

Structure and molecular analysis of RGR1, a gene required for glucose repression of Saccharomyces cerevisiae.

1990 • 87 citations

Constitutive expression of the yeast HEM1 gene is actually a composite of activation and repression.

1987 • 85 citations

Co-ordinate control of synthesis of mitochondrial and non-mitochondrial hemoproteins: a binding site for the HAP1 (CYP1) protein in the UAS region of the yeast catalase T gene (CTT1).

1988 • 85 citations

Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4.

1991 • 83 citations

Differential regulation of the duplicated isocytochrome c genes in yeast.

1984 • 82 citations

Purification of a yeast centromere-binding protein that is able to distinguish single base-pair mutations in its recognition site.

1989 • 81 citations

Mutational analysis of the SNF3 glucose transporter of Saccharomyces cerevisiae.

1990 • 80 citations

Subunit interaction in the CCAAT-binding heteromeric complex is mediated by a very short alpha-helix in HAP2.

1994 • 80 citations

Isolation of Saccharomyces cerevisiae mutants constitutive for invertase synthesis

1986 • 80 citations

Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis

1981 • 79 citations

HAP1 and ROX1 form a regulatory pathway in the repression of HEM13 transcription in Saccharomyces cerevisiae.

1992 • 79 citations

The residual enzymatic phosphorylation activity of hexokinase II mutants is correlated with glucose repression in Saccharomyces cerevisiae.

1989 • 78 citations

A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1.

1991 • 77 citations

Glucose-induced hyperaccumulation of cyclic AMP and defective glucose repression in yeast strains with reduced activity of cyclic AMP-dependent protein kinase.

1990 • 77 citations

Common protein-binding sites in the 5'-flanking regions of human genes for cytochrome c1 and ubiquinone-binding protein.

1990 • 77 citations

Role of multifunctional autonomously replicating sequence binding factor 1 in the initiation of DNA replication and transcriptional control in Saccharomyces cerevisiae.

1992 • 76 citations

The Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae HAP2 reveals selective and stringent conservation of the small essential core protein domain.

1991 • 74 citations

Nuclear mutations in the petite-negative yeast Schizosaccharomyces pombe allow growth of cells lacking mitochondrial DNA.

1992 • 74 citations

An ARS/silencer binding factor also activates two ribosomal protein genes in yeast

1989 • 74 citations

Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae.

1992 • 73 citations

Isolation and DNA-binding characteristics of a protein involved in transcription activation of two divergently transcribed, essential yeast genes.

1989 • 72 citations

Structure and regulation of KGD2, the structural gene for yeast dihydrolipoyl transsuccinylase.

1990 • 72 citations

Signal transduction in yeast mating: Receptors, transcription factors, and the kinase connection

1991 • 71 citations

A hypoxic consensus operator and a constitutive activation region regulate the ANB1 gene of Saccharomyces cerevisiae.

1990 • 71 citations

Elements involved in S-adenosylmethionine-mediated regulation of the Saccharomyces cerevisiae MET25 gene.

1989 • 70 citations

Differential accumulation of two apo-iso-cytochromes c in processing mutants of yeast.

1982 • 69 citations

Isolation and characterization of nuclear genes coding for subunits of the yeast ubiquinol-cytochrome c reductase complex

1982 • 67 citations

Organization of the regulatory region of the yeast CYC7 gene: multiple factors are involved in regulation.

1987 • 67 citations

Characterization of Hex2 protein, a negative regulatory element necessary for glucose repression in yeast

1991 • 67 citations

New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae.

1991 • 66 citations

Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1(HAP1) activator binds to the CYB2 upstream activation site UAS1-B2.

1991 • 66 citations

Signal transduction in yeast mating: Receptors, transcription factors, and the kinase connection

1991 • 66 citations

A yeast protein with homology to the β-subunit of G proteins is involved in control of heme-regulated and catabolite-repressed genes

1991 • 65 citations

Structure and regulation of SDH3, the yeast gene encoding the cytochrome b560 subunit of respiratory complex II.

1994 • 64 citations

The DAL7 promoter consists of multiple elements that cooperatively mediate regulation of the gene's expression.

1989 • 62 citations

CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast

1988 • 61 citations

The ANB1 locus of Saccharomyces cerevisiae encodes the protein synthesis initiation factor eIF-4D.

1990 • 61 citations

Structural analysis of two genes encoding divergent forms of yeast cytochrome c oxidase subunit V.

1987 • 59 citations

Isolation and characterization of the regulatory HEX2 gene necessary for glucose repression in yeast

1987 • 58 citations

DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast

1991 • 58 citations

Mutations that alter transcriptional activation but not DNA binding in the zinc finger of yeast activator HAPI

1989 • 58 citations

TFIIB or not TFIIB?

1991 • 53 citations

The OBF1 protein and its DNA-binding site are important for the function of an autonomously replicating sequence in Saccharomyces cerevisiae.

1989 • 52 citations

Sequence of the HAP3 transcription factor of Kluyveromyces lactis predicts the presence of a novel 4-cysteine zinc-finger motif

1994 • 50 citations

Differential regulation of the transcript levels of some nuclear‐encoded and mitochondrial‐encoded respiratory‐chain components in response to growth activation

1992 • 50 citations

The Nucleotide Sequence of the LPD1 Gene Encoding Lipoamide Dehydrogenase in Saccharomyces cerevisiae: Comparison between Eukaryotic and Prokaryotic Sequences for Related Enzymes and Identification of Potential Upstream Control Sites

1988 • 49 citations

A mutation in the yeast heat-shock factor gene causes temperature-sensitive defects in both mitochondrial protein import and the cell cycle.

1991 • 48 citations

Cyclic AMP may not be involved in catabolite repression in Saccharomyces cerevisiae: evidence from mutants unable to synthesize it

1983 • 48 citations

Release of two Saccharomyces cerevisiae cytochrome genes, COX6 and CYC1, from glucose repression requires the SNF1 and SSN6 gene products.

1990 • 48 citations

Analysis of URSG-mediated glucose repression of the GAL1 promoter of Saccharomyces cerevisiae.

1992 • 48 citations

Interaction between the yeast mitochondrial and nuclear genomes influences the abundance of novel transcripts derived from the spacer region of the nuclear ribosomal DNA repeat.

1989 • 46 citations

ABF1 is a phosphoprotein and plays a role in carbon source control of COX6 transcription in Saccharomyces cerevisiae.

1992 • 46 citations

Regulation of Yeast COX6 by the General Transcription Factor ABF1 and Separate HAP2- and Heme-Responsive Elements

1992 • 44 citations

Elements involved in oxygen regulation of the Saccharomyces cerevisiae CYC7 gene.

1987 • 44 citations

Global regulation of mitochondrial biogenesis in Saccharomyces cerevisiae: ABF1 and CPF1 play opposite roles in regulating expression of the QCR8 gene, which encodes subunit VIII of the mitochondrial ubiquinol-cytochrome c oxidoreductase.

1992 • 43 citations

Positive regulation of the LPD1 gene of Saccharomyces cerevisine by the HAP2/HAP3/HAP4 activation system

1992 • 40 citations

Mitochondrial control of sugar utilization in Saccharomyces cerevisiae

1978 • 39 citations

Structure and regulation of a nuclear gene in Saccharomyces cerevisiae that specifies MRP13, a protein of the small subunit of the mitochondrial ribosome.

1988 • 38 citations

Kluyveromycescontains a functional ABF1-homologue

1992 • 38 citations

Differential effectiveness of yeast cytochrome c oxidase subunit genes results from differences in expression not function.

1987 • 38 citations

Inactivation of the gene encoding the 14‐kDa subunit VII of yeast ubiquinol

1989 • 37 citations

IMP1/imp1: A GENE INVOLVED IN THE NUCLEO-MITOCHONDRIAL CONTROL OF GALACTOSE FERMENTATION IN SACCHAROMYCES CEREVISIAE

1981 • 37 citations

Upstream activation and repression elements control transcription of the yeast COX5b gene.

1990 • 37 citations

Regulation of the expression of iso 2-cytochrome c gene in S. cerevisiae: cloning of the positive regulatory gene CYP1 and identification of the region of its target sequence on the structural gene CYP3

1985 • 37 citations

The multifunctional protein OBF1 is phosphorylated at serine and threonine residues in Saccharomyces cerevisiae.

1991 • 36 citations

Transposable element-mediated enhancement of gene expression in Saccharomyces cerevisiae involves sequence-specific binding of a trans-acting factor.

1988 • 34 citations

Demarcation of a sequence involved in mediating catabolite repression of the gene for the 11 kDa subunit VIII of ubiquinol-cytochrome c oxidoreductase in Saccharomyces cerevisiae

1988 • 33 citations

The extended promoter of the gene encoding ribosomal protein S33 in yeast consists of multiple protein binding elements

1989 • 31 citations

Control of the Saccharomyces cerevisiae regulatory gene PET494: transcriptional repression by glucose and translational induction by oxygen.

1989 • 31 citations

REGULATION OF REPRESSIBLE ACID PHOSPHATASE BY CYCLIC AMP IN SACCHAROMYCES CEREVISIAE

1984 • 30 citations

Regulation of yeast COX6 by the general transcription factor ABF1 and separate HAP2- and heme-responsive elements.

1992 • 29 citations

Expression of the gene encoding subunit II of yeast QH2: Cytochrome c oxidoreductase is regulated by multiple factors

1990 • 27 citations

Identification of an upstream activation sequence and other cis-acting elements required for transcription of COX6 from Saccharomyces cerevisiae.

1989 • 27 citations

Saccharomyces cerevisiae positive regulatory gene PET111 encodes a mitochondrial protein that is translated from an mRNA with a long 5' leader.

1987 • 27 citations

Global regulators of chromosome function in yeast

1992 • 26 citations

MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants

1994 • 24 citations

Internal deletions in the yeast transcriptional activator HAP1 have opposite effects at two sequence elements.

1990 • 23 citations

The multifunctional regulatory proteins ABF1 and CPF1 are involved in the formation of a nuclease‐hypersensitive region in the promoter of the QCR8 gene

1993 • 21 citations

Heat shock and stationary phase induce transcription of the Saccharomyces cerevisiae iso-2 cytochrome c gene

1991 • 20 citations

Multi‐functional DNA proteins in yeast: The factors GFI and GFII are identical to the ARS‐binding factor ABFI and the centromere‐binding factor CPF1 respectively

1991 • 19 citations

Isolation and characterisation of the linked genes, FPS1 and QCR8, coding for farnesyl-diphosphate synthase and the 11 kDa subunit VIII of the mitochondrial bc1-complex in the yeast Kluyveromyces lactis

1994 • 19 citations

IMP2, a nuclear gene controlling the mitochondrial dependence of galactose, maltose and raffinose utilization in Saccharomyces cerevisiae

1992 • 19 citations

Oxygen-dependent upstream activation sites of Saccharomyces cerevisiae cytochrome c genes are related forms of the same sequence.

1988 • 19 citations

Expression of yeast cytochrome C1 is controlled at the transcriptional level by glucose, oxygen and haem

1992 • 18 citations

Effects of hap mutations on heme and cytochrome formation in yeast

1990 • 17 citations

The CCS1 gene from Saccharomyces cerevisiae which is involved in mitochondrial functions is identified as IRA2 an attenuator of RAS1 and RAS2 gene products

1992 • 16 citations

A point mutation in the CYC1 UAS1 creates a new combination of regulatory elements that activate transcription synergistically.

1989 • 15 citations

Transcriptional regulation of the cell cycle-dependent thymidylate synthase gene of Saccharomyces cerevisiae.

1988 • 15 citations

Corruption Scandal Reaches Academe

1994 • 15 citations

Isolation and genetic study of Triethyltin-resistant mutants of Saccharomyces cerevisiae

1990 • 13 citations

Multifunctional DNA-binding proteins in yeast.

1992 • 13 citations

The yeast IMP1 gene is allelic to GAL2

1991 • 13 citations

Regulation of mitochondrial transcription during the stringent response in yeast

1992 • 12 citations

Mitochondrial modifications in a single nuclear mutant of Saccharomyces cerevisiae affected in cAMP-dependent protein phosphorylation

1990 • 12 citations

Effect of mitochondrial functions on synthesis of yeast cytochrome c

1980 • 8 citations

The transactivator GAL4: Co‐activators, adaptors and chromatin

1991 • 7 citations

The N-Terminal TPR Region Is the Functional Domain of SSN6, a Nuclear Phosphoprotein ofSaccharomyces cerevisiae:

1992 • 1 citations