The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Principles and procedures of statistics.

1960 • 22,587 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Principles and Procedures of Statistics

1961 • 18,011 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

1974 • 1,410 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Arachidonic acid metabolism in polymorphonuclear leukocytes

1979 • 812 citations

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

1983 • 705 citations

On the Specificity of the Oxygenation of Unsaturated Fatty Acids Catalyzed by Soybean Lipoxidase

1967 • 660 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Amino acid sequence of human tumor derived angiogenin

1985 • 357 citations

Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid.

1980 • 330 citations

Stimulation and Blockade of Prostaglandin Biosynthesis

1971 • 286 citations

Purification of heparin-binding growth factors

1986 • 279 citations

Demonstration of vasoproliferative activity from mammalian retina.

1980 • 272 citations

R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet.

1985 • 270 citations

Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes.

1985 • 220 citations

Platelet activating factor. Stimulation of the lipoxygenase pathway in polymorphonuclear leukocytes by 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine.

1982 • 194 citations

The effects of bombesin on polyphosphoinositide and calcium metabolism in Swiss 3T3 cells.

1987 • 175 citations

Preparation and assay of monohydroxy-eicosatetraenoic acids

1980 • 173 citations

Human airway monohydroxyeicosatetraenoic acid generation and mucus release.

1983 • 166 citations

Differential effects of calmodulin antagonists on phospholipases A2 and C in thrombin-stimulated platelets.

1981 • 152 citations

Induction of protein kinase C activation and Ca²⁺ mobilization by fibroblast growth factor in Swiss 3T3 cells

1985 • 148 citations

Protein kinases in signal transduction

1984 • 123 citations

Inositol lipid metabolism in dividing and differentiating cells

1982 • 119 citations

Leukotriene B4 and 12-Hydroxyeicosatetraenoic Acid Stimulate Epidermal Proliferation In Vivo in the Guinea Pig

1985 • 115 citations

Local anesthetics, chlorpromazine and propranolol inhibit stimulus-activation of phospholipase A2 in human platelets.

1979 • 113 citations

15-Hydroxy-5,8,11,13-eicosatetraenoic acid inhibits human vascular cyclooxygenase. Potential role in diabetic vascular disease.

1986 • 98 citations

Eicosanoid effects on cell proliferation in vitro: Relevance to atherosclerosis

1984 • 74 citations

Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds

1981 • 69 citations

Thin-layer chromatography of polyphosphoinositides from platelet extracts: Interference by an unknown phospholipid.

1985 • 68 citations

A New View of Receptor Action

1984 • 62 citations

Toward a New Understanding of Vascular Proliferative Disease in Children

1984 • 58 citations

12-Hydroxyeicosatetraenoic acid reduces prostacyclin production by endothelial cells

1986 • 56 citations

Inhibition of human malignant neuroblastoma cell DNA synthesis by lipoxygenase metabolites of arachidonic acid.

1985 • 52 citations

Formation of 6-oxoprostaglandin F1 alpha, 6,15-dioxoprostaglandin F1 alpha, and monohydroxyicosatetraenoic acids from arachidonic acid by fetal calf aorta and ductus arteriosus.

1982 • 46 citations

The effect of precursors, products, and product analogs of prostaglandin cyclooxygenase upon iris sphincter muscle

1978 • 46 citations

Synergism between diacylglycerols and calcium ionophore in the induction of human B cell proliferation mimics the inositol lipid polyphosphate breakdown signals induced by crosslinking surface immunoglobulin

1985 • 43 citations

Endothelial cell proliferation may be mediated VIA the production of endogenous lipoxygenase metabolites

1987 • 39 citations

Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages

1985 • 35 citations

A platelet factor stimulating the proliferation of vascular endothelial cells

1985 • 32 citations

Inhibition of phytohemagglutinin-induced lymphocyte mitogenesis by lipoxygenase metabolites of arachidonic acid: structure-activity relationships.

1984 • 29 citations

[1] Preparation of selectively labeled phosphatidylinositol and assay of phosphatidylinositol-specific phospholipase C

1982 • 21 citations

The effect of 5-hydroxyeicosatetraenoic acid on the proliferation of granulocyte progenitors and embryonic fibroblasts of the chick

1985 • 11 citations

Decreased Cyclic Guanosine 3´,5´ Monophosphate and Guanylate Cyclase Activity in Leprechaunism: Evidence for a Postreceptor Defect

1986 • 11 citations

15–HYDROXYEICOSATETRAENOIC ACID (15–HETE) PROMOTES MIGRATION OF HUMAN RETINAL MICROVESSEL ENDOTHELIAL CELLS (HME) IN VITRO

1987 • 4 citations