12-Hydroxyeicosatetraenoic acid reduces prostacyclin production by endothelial cells

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

1974 • 1,410 citations

Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells

1985 • 1,237 citations

Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

1979 • 297 citations

15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase.

1980 • 195 citations

Modulation of human neutrophil function by monohydroxy-eicosatetraenoic acids.

1980 • 172 citations

Prostacyclin and arterial wall biology.

1982 • 164 citations

Effect of fatty acid modification on prostacyclin production by cultured human endothelial cells.

1980 • 155 citations

Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.

1980 • 118 citations

Unique aspects of the modulation of human neutrophil function by 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid

1980 • 112 citations

Mono- and dihydroxyeicosatetraenoic acids alter calcium homeostasis in rabbit neutrophils.

1981 • 110 citations

Uptake and metabolism of monohydroxy-eicosatetraenoic acids by macrophages.

1982 • 93 citations

Esterification of an endogenously synthesized lipoxygenase product into granulocyte cellular lipids

1981 • 93 citations

Eicosanoid effects on cell proliferation in vitro: Relevance to atherosclerosis

1984 • 74 citations

Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETEs) A novel pharmacological mechanism for regulating free fatty acid release

1985 • 72 citations

Transformation of arachidonic acid into monohydroxy‐eicosatetraenoic acids by mouse peritoneal macrophages

1981 • 71 citations

Formation of monohydroxyeicosatetraenoic acids from arachidonic acid by cultured rabbit aortic smooth muscle cells

1983 • 70 citations

Prostacyclin release from cultured and ex vivo bovine vascular endothelium. Studies with thrombin, arachidonic acid, and ionophore A23187.

1981 • 69 citations

Linoleic acid metabolism and prostaglandin production by cultured bovine pulmonary artery endothelial cells.

1982 • 68 citations

[61] Separation of arachidonic acid metabolites by high-pressure liquid chromatography

1982 • 63 citations

Esterification of monohydroxyfatty acids into the lipids of a macrophage cell line

1983 • 60 citations

Possible inhibitory function of endogenous 15-hydroperoxyeicosatetraenoic acid on prostacyclin formation in bovine aortic endothelial cells

1986 • 53 citations

Arachidonic acid metabolites and endothelial injury: studies with cultures of human endothelial cells.

1985 • 53 citations

Inhibition of human malignant neuroblastoma cell DNA synthesis by lipoxygenase metabolites of arachidonic acid.

1985 • 52 citations

Stimulation of human endothelial cell prostacyclin synthesis by select leukotrienes.

1984 • 45 citations

Arachidonic acid availability and prostacyclin production by cultured human endothelial cells.

1983 • 45 citations

Specific incorporation of 5-hydroxy-6,8,11,14-eicosatetraenoic acid into phosphatidylcholine in human endothelial cells

1986 • 45 citations

Arachidonic acid metabolism in isolated pancreatic islets

1985 • 42 citations

Increased production of lipoxygenase products by cholesterol-rich mouse macrophages

1985 • 40 citations

Incorporation of platelet and leukocyte lipoxygenase metabolites by cultured vascular cells

1986 • 31 citations

Age-related increase in the migration of aortic smooth muscle cells induced by 12--hydroxy-5,8,10,14-eicosatetraenoic acid

1984 • 16 citations

Time-dependent inhibition of the cyclooxygenase pathway by 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid

1985 • 15 citations

Differential effects of lipoxygenase products on FMLP and LTB₄ evoked neutrophil aggregation

1985 • 14 citations

Impairment of citrulline synthesis during late pregnancy and lactation in rats

1985 • 9 citations