Inhibition of phytohemagglutinin-induced lymphocyte mitogenesis by lipoxygenase metabolites of arachidonic acid: structure-activity relationships.

Arachidonic acid metabolism in polymorphonuclear leukocytes

1979 • 812 citations

Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

1979 • 652 citations

Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid.

1980 • 330 citations

Leukotrienes and other Lipoxygenase Products

1983 • 319 citations

The Lipoxygenase of Reticulocytes

1979 • 280 citations

Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid.

1982 • 202 citations

15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase.

1980 • 195 citations

The identification of hydroxy fatty acids in psoriatic skin

1983 • 171 citations

In vitro stimulation of murine spleen cells using a microculture system and a multiple automated sample harvester

1973 • 165 citations

Preparation and purification of arachidonic acid hydroperoxides of biological importance

1979 • 161 citations

Leukotrienes and other lipoxygenase products

1986 • 149 citations

Selective feed-back inhibition of the 5-lipoxygenation of arachidonic acid in human T-lymphocytes

1981 • 146 citations

Regulation of T-lymphocyte mitogenesis by the leukocyte product 15-hydroxy-eicosatetraenoic acid (15-HETE)

1982 • 109 citations

12-L-hydroxy-5,8,10,14-eicosatetraenoic acid, a chemotactic fatty acid, is incorporated into neutrophil phospholipids and triglyceride

1979 • 92 citations

Regulation of leukocyte and platelet lipoxygenases by hydroxyeicosanoids

1982 • 89 citations

Characterization of 11-HETE and 15-HETE, together with prostacyclin, as major products of the cyclooxygenase pathway in cultured rat aorta smooth muscle cells.

1983 • 85 citations

Measurement of prostaglandins, thromboxanes, prostacyclin and their metabolites by gas liquid chromatography--mass spectrometry.

1978 • 73 citations

Esterification of monohydroxyfatty acids into the lipids of a macrophage cell line

1983 • 60 citations

Lipid metabolism in cultured cells. Synthesis of vasoactive thromboxane A2 from [14C]arachidonic acid culture lung fibroblasts.

1978 • 58 citations

Cyclic nucleotides in mitogen-induced lymphocyte proliferation

1982 • 53 citations

The effect of precursors, products, and product analogs of prostaglandin cyclooxygenase upon iris sphincter muscle

1978 • 46 citations

Phorbol myristate acetate stimulation of lymphocyte guanylate cyclase and cyclic guanosine 3':5'-monophosphate phosphodiesterase and reduction of adenylate cyclase.

1983 • 37 citations

Role of lipoxygenases in regulation of PHA and phorbol ester-induced mitogenesis.

1982 • 20 citations

Receptor binding in various tissues of PGE2, PGF2α and sulprostone, a novel PGE2-derivative

1979 • 15 citations