3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in a rat mast cell line. Impairment of tyrosine kinase-dependent signal transduction and the subsequent degranulation response

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Fc Receptors

1991 • 1,220 citations

Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1989 • 978 citations

EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling

1989 • 784 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

CSK: a protein-tyrosine kinase involved in regulation of src family kinases.

1991 • 522 citations

Posttranslational modification of proteins by isoprenoids in mammalian cells

1990 • 515 citations

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1992 • 503 citations

Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis

1991 • 449 citations

Discovery, biochemistry and biology of lovastatin

1988 • 348 citations

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

1992 • 306 citations

The Receptor with High Affinity for IgE

1992 • 266 citations

Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

1990 • 234 citations

Fc epsilon RI-mediated tyrosine phosphorylation and activation of the 72-kDa protein-tyrosine kinase, PTK72, in RBL-2H3 rat tumor mast cells.

1992 • 231 citations

The Src family of tyrosine protein kinases in hemopoietic signal transduction

1992 • 221 citations

IgE-induced tyrosine phosphorylation of phospholipase C-gamma 1 in rat basophilic leukemia cells.

1991 • 184 citations

Structure-function relationships in the mast cell high affinity receptor for IgE. Role of the cytoplasmic domains and of the beta subunit.

1991 • 181 citations

Tyrosine phosphorylation is required for mast cell activation by Fc epsilon RI cross-linking.

1992 • 101 citations

High-affinity IgE receptor-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells induces early and late protein-tyrosine phosphorylations.

1992 • 88 citations

Expression and Interactions of the Src Family of Tyrosine Protein Kinases in T Lymphocytes

1991 • 83 citations

Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3)

1991 • 72 citations

Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.

1988 • 69 citations

[37] Radiochemical sequence analysis of biosynthetically labeled proteins

1983 • 67 citations

Antigen- and ionophore-induced signal transduction in rat basophilic leukemia cells involves protein tyrosine phosphorylation.

1991 • 57 citations

Tyrosine phosphorylation of phospholipase C γ₁ couples the FCη receptor mediated signal to mast cells secretion

1992 • 50 citations

Association of protein-tyrosine kinase with phospholipase C-gamma 1 in bone marrow-derived mouse mast cells.

1992 • 32 citations

Role of isoprenoid metabolism in IgE receptor-mediated signal transduction.

1991 • 31 citations

Isoprenoid pathway activity is required for IgE receptor-mediated, tyrosine kinase-coupled transmembrane signaling in permeabilized RBL-2H3 rat basophilic leukemia cells.

1991 • 25 citations