rap1B, a cAMP-dependent protein kinase substrate, associates with the platelet cytoskeleton.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins

1990 • 1,037 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

ras GTPase activating protein: Signal transmitter and signal terminator

1989 • 621 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

1989 • 529 citations

Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis.

1989 • 462 citations

Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

1984 • 403 citations

Identification of membrane proteins mediating the interaction of human platelets

1980 • 383 citations

The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

1986 • 281 citations

ras oncogenes: their role in neoplasia

1990 • 244 citations

Possible involvement of two proteins (phosphoprotein and CD9(p24)) in regulation of platelet calcium fluxes

1985 • 243 citations

Identification of actin-binding protein as the protein linking the membrane skeleton to glycoproteins on platelet plasma membranes.

1985 • 236 citations

Structural and functional properties of ras proteins

1989 • 211 citations

Identification of a membrane skeleton in platelets.

1988 • 161 citations

Effects of collagen, ionophore A23187 and prostaglandin E1 on the phosphorylation of specific proteins in blood platelets

1979 • 150 citations

Nucleotide sequence of a human cDNA encoding aras-related protein (rap1B)

1988 • 145 citations

A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets.

1989 • 141 citations

Regulation of the intracellular calcium level in human blood platelets: Cyclic adenosine 3′,5′-monophosphate dependent phosphorylation of a 22 000 dalton component in isolated Ca2+-accumulating vesicles

1979 • 138 citations

Phosphorylation of smg p21, a ras p21-like GTP-binding Protein, by Cyclic AMP-dependent Protein Kinase in a Cell-free System and in Response to Prostaglandin E1 in Intact Human Platelets

1989 • 110 citations

Rap1-b is phosphorylated by protein kinase a in intact human platelets

1990 • 90 citations

Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products

1988 • 88 citations

Cyclic AMP-dependent Phosphorylation of Glycoprotein Ib Inhibits Collagen-induced Polymerization of Actin in Platelets

1989 • 84 citations

The ras superfamily proteins

1988 • 79 citations

Recycling of platelet phosphorylation and cytoskeletal assembly.

1984 • 73 citations

Rapid sulfopropyl-disk chromatographic purification of bovine and human thrombin

1986 • 73 citations

Identification of glycoprotein Ib beta as one of the major proteins phosphorylated during exposure of intact platelets to agents that activate cyclic AMP-dependent protein kinase.

1987 • 68 citations

Molecular cloning of p21B and identification of p21 purified from bovine brain and human platelets as p21B

1990 • 53 citations

Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products

1988 • 52 citations

Partial purification and characterization of thrombolamban, A 22,000 dalton cAMP-dependent protein kinase substrate in platelets

1987 • 51 citations

Glycoprotein Ib in the triton-insoluble (cytoskeletal) fraction of blood platelets

1984 • 49 citations

Regulation of human platelet membrane Ca2+ transport by cAMP- and calmodulin-dependent phosphorylation

1987 • 45 citations

Thrombolamban, the 22-kDa platelet substrate of cyclic AMP-dependent protein kinase, is immunologically homologous with the Ras family of GTP-binding proteins.

1990 • 38 citations

Low Mr GTP-binding proteins in human platelets: Cyclic AMP-dependent protein kinase phosphorylates m22KG(I) in membrane but not c21KG in cytosol

1989 • 37 citations

Modulation of Ca2+ fluxes in isolated platelet vesicles: effects of cAMP-dependent protein kinase and protein kinase inhibitor on Ca2+ sequestration and release

1987 • 32 citations

ras p21 deletion mutants and monoclonal antibodies as tools for localization of regions relevant to p21 function.

1986 • 29 citations

Aggregation-related association of lipid with the cytoskeleton of rabbit and human platelets prelabeled with [3H]palmitic acid. Similar effects of adenosine diphosphate- and thrombin-induced aggregation.

1988 • 16 citations

Cyclic amp-dependent protein kinase does not increase calcium transport in platelet microsomes

1989 • 14 citations