Identification of glycoprotein Ib beta as one of the major proteins phosphorylated during exposure of intact platelets to agents that activate cyclic AMP-dependent protein kinase.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new solid-state reagent to iodinate proteins

1982 • 893 citations

Platelets in Biology and Pathology

1981 • 644 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

1977 • 451 citations

DIPYRIDAMOLE AND OTHER PHOSPHODIESTERASE INHIBITORS ACT AS ANTITHROMBOTIC AGENTS BY POTENTIATING ENDOGENOUS PROSTACYCLIN

1978 • 392 citations

Molecular Defects in Interactions of Platelets with the Vessel Wall

1984 • 381 citations

BATTERED BABIES—HOW MANY DO WE MISS?

1970 • 365 citations

Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity

1986 • 354 citations

Thrombosis and haemostasis

1988 • 327 citations

Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate and protein kinase

1977 • 311 citations

Guanine nucleotides decrease the free [Ca²⁺] required for secretion of serotonin from permeabilized blood platelets

1984 • 236 citations

Identification of actin-binding protein as the protein linking the membrane skeleton to glycoproteins on platelet plasma membranes.

1985 • 236 citations

Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membrane

1985 • 229 citations

The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin)

1983 • 217 citations

Role of phosphorylation in mediating the association of myosin with the cytoskeletal structures of human platelets.

1982 • 195 citations

Biochemistry of Platelets

1986 • 194 citations

Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane

1987 • 191 citations

Additional glycoprotein defects in Bernard-Soulier's syndrome: confirmation of genetic basis by parental analysis

1983 • 186 citations

Platelet Membrane Glycoproteins

1985 • 184 citations

Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein Ib.

1985 • 173 citations

On the association of glycoprotein Ib and actin-binding protein in human platelets.

1985 • 165 citations

Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

1981 • 151 citations

Effects of collagen, ionophore A23187 and prostaglandin E1 on the phosphorylation of specific proteins in blood platelets

1979 • 150 citations

Human platelet secretion and aggregation induced by calcium ionophores. Inhibition by PGE1 and dibutyryl cyclic AMP.

1975 • 127 citations

Platelets: Cellular Response Mechanisms and their Biological Significance

1981 • 102 citations

Characterization of platelet extracts before and after stimulation with respect to the possible role of profilactin as microfilament precursor

1981 • 100 citations

Activation of platelets by alpha-thrombin is a receptor-mediated event. D-phenylalanyl-L-prolyl-L-arginine chloromethyl ketone-thrombin, but not N alpha-tosyl-L-lysine chloromethyl ketone-thrombin, binds to the high affinity thrombin receptor.

1986 • 92 citations

Subcellular distribution of the different platelet proteins phosphorylated on exposure of intact platelets to ionophore A23187 or to prostaglandin E1. Possible role of a membrane phosphopolypeptide in the regulation of calcium-ion transport

1979 • 83 citations

The activation and dissociation of a native high molecular weight form of rabbit skeletal muscle phosphorylase phosphatase by endogenous CA2+-dependent proteases.

1979 • 83 citations

Platelet thrombin receptors. Binding of alpha-thrombin is coupled to signal generation by a chymotrypsin-sensitive mechanism.

1980 • 82 citations

Reversal of thrombin-induced myosin phosphorylation and the assembly of cytoskeletal structures in platelets by the adenylate cyclase stimulants prostaglandin D2 and forskolin.

1983 • 76 citations

Recycling of platelet phosphorylation and cytoskeletal assembly.

1984 • 73 citations

Thrombin Interactions with Platelet Membrane Proteins^a

1986 • 49 citations

Glycoprotein Ib in the triton-insoluble (cytoskeletal) fraction of blood platelets

1984 • 49 citations

Glycoprotein Ibβ is the only phosphorylated major membrane glycoprotein in human platelets

1986 • 32 citations

Relationship between phosphorylation of blood platelet proteins and secretion of platelet granule constituents II. Effects of different inhibitors

1978 • 30 citations