Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells

Inhibition of NF-κB by Sodium Salicylate and Aspirin

1994 • 1,743 citations

Pathogenetic Mechanisms of Septic Shock

1993 • 1,577 citations

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 • 1,233 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

The Structural Biology of Expression and Function of Tissue Factor

1991 • 563 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation

1992 • 501 citations

Nuclear factor kappa B, a mediator of lipopolysaccharide effects

1993 • 476 citations

The inducible transcription factor NF-κB: structure-function relationship of its protein subunits

1993 • 429 citations

Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody.

1991 • 428 citations

Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.

1994 • 405 citations

Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites.

1991 • 373 citations

Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade

1987 • 318 citations

Increased Tissue Thromboplastin Activity in Monocytes of Patients with Meningococcal Infection: Related to an Unfavourable Prognosis

1983 • 311 citations

Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin.

1989 • 294 citations

Initiation of Coagulation by Tissue Facto

1988 • 258 citations

Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells

1993 • 239 citations

Modes of action of aspirin-like drugs.

1985 • 218 citations

Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity

1990 • 199 citations

Detection and characterization of cellular EGR-1 binding to its recognition site

1993 • 193 citations

Effect of ibuprofen in patients with severe sepsis

1991 • 180 citations

A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.

1989 • 171 citations

Depletion of extrinsic pathway inhibitor (EPI) sensitizes rabbits to disseminated intravascular coagulation induced with tissue factor: evidence supporting a physiologic role for EPI as a natural anticoagulant.

1991 • 170 citations

Thrombosis and cancer

1987 • 170 citations

Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis

1991 • 162 citations

Monoclonal antibody analysis of purified and cell-associated tissue factor

1988 • 161 citations

The Genesis of Ores

1991 • 157 citations

A set of inducible genes expressed by activated human monocytic and endothelial cells contain kappa B-like sites that specifically bind c-Rel-p65 heterodimers.

1994 • 155 citations

Simplified northern blot hybridization using 5% sodium dodecyl sulfate.

1990 • 149 citations

Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccharide.

1991 • 143 citations

Aspirin and the Salicylates

1984 • 128 citations

Lipopolysaccharide Induction of Tissue Factor Gene Expression in Monocytic Cells Is Mediated by Binding of c-Rel/p65 Heterodimers to a κB-Like Site

1994 • 118 citations

Pseudomonas Septicemia with Intravascular Clotting Leading to the Generalized Shwartzman Reaction

1964 • 82 citations

Protease inhibitors block lipopolysaccharide induction of tissue factor gene expression in human monocytic cells by preventing activation of c-Rel/p65 heterodimers

1994 • 58 citations

Positive and Negative Regulation of Transcription and Cell Growth Mediated by the EGR Family of Zinc‐Finger Gene Products^a

1993 • 51 citations

The stable prostacyclin analog, iloprost, and prostaglandin E1 inhibit monocyte procoagulant activity in vitro

1991 • 49 citations

Tissue factor gene expression in acute myeloblastic leukemia

1989 • 45 citations

Role of leukocytes in the activation of intravascular coagulation in patients with septicemia

1991 • 43 citations

Effects of Salsalate (Nonacetylated Salicylate) and Aspirin on Serum Prostaglandins in Humans

1985 • 37 citations

Studies on the beneficial effects of Aspirin in endotoxic shock

1983 • 33 citations

Ibuprofen intervention in canine septic shock: Reduction of pathophysiology without decreased cytokines

1992 • 31 citations

Pentoxifylline Inhibition of Procoagulant Activity Generated by Activated Mononuclear Phagocytes

2015 • 28 citations

Characterization of nuclear protein binding to the interferon‐γ promoter in quiescent and activated human T cells

1992 • 27 citations

The Clinical Pharmacology of Anti-Inflammatory Agents

1986 • 25 citations

Pentoxifylline inhibits the expression of tissue factor mRNA in endotoxin‐activated human monocytes

1993 • 21 citations

Endotoxic shock in the primate: Effects of aspirin and dipyridamole administration

1981 • 21 citations

Inhibition of lipoxygenase (LOX) or of cyclooxygenase (COX) improves survival of rats in endotoxin shock.

1988 • 4 citations