Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Calcium Signaling in Neurons: Molecular Mechanisms and Cellular Consequences

1995 • 1,421 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

Genetic dissection of consolidated memory in Drosophila

1994 • 901 citations

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

1993 • 817 citations

Molecular Physiology of the Regulation of Hepatic Gluconeogenesis and Glycolysis

1992 • 816 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

CREB as a Memory Modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in drosophila

1995 • 639 citations

cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase.

1991 • 552 citations

Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

1994 • 542 citations

Regulation of camp-inducible genes by creb

1990 • 416 citations

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

1994 • 394 citations

Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

1988 • 391 citations

Differentiation-induced Gene Expression in 3T3-L1 Preadipocytes

1989 • 373 citations

Specific temporal and spatial distribution of JUN, FOS, and KROX‐24 proteins in spinal neurons following noxious transsynaptic stimulation

1991 • 338 citations

Behavioral and anatomical deficits in mice homozygous for a modified ?-amyloid precursor protein gene

1994 • 307 citations

Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant

1991 • 302 citations

Functional analysis of alternatively spliced tyrosinase gene transcripts.

1988 • 275 citations

cAMP Evokes Long-Term Facilitation in Aplysia Sensory Neurons That Requires New Protein Synthesis

1988 • 265 citations

Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in aplysia sensory neurons

1992 • 253 citations

Transcription factors: a new family gathers at the cAMP response site

1990 • 244 citations

Characterization of a bipartite activator domain in transcription factor CREB

1990 • 228 citations

Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.

1996 • 221 citations

Regulation of Cyclic AMP Response Element‐Binding Protein (CREB) Phosphorylation by Acute and Chronic Morphine in the Rat Locus Coeruleus

1992 • 203 citations

Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase.

1987 • 194 citations

A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung.

1992 • 189 citations

Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes.

1992 • 189 citations

Induction of immediate early gene encoded proteins in the rat hippocampus after bicuculline-induced seizures: Differential expression of KROX-24, FOS and JUN proteins

1992 • 142 citations

Identification and functional characterisation of the cellular activating transcription factor 43 (ATF-43) protein

1991 • 123 citations

Calcium/Calmodulin-Dependent Protein Kinase Types II and IV Differentially Regulate CREB-Dependent Gene Expression

1994 • 123 citations

The promoter of the gene encoding 3',5'-cyclic adenosine monophosphate (cAMP) response element binding protein contains cAMP response elements: evidence for positive autoregulation of gene transcription.

1993 • 104 citations

Determination of messenger RNA 5′-ends by reverse transcription of the cap structure

1993 • 94 citations

Transcriptional response to cAMP in brain: Specific distribution and induction of CREM antagonists

1993 • 86 citations

Striking homology of the ‘Variable’ N-terminal as well as the ‘conserved core’ domains of the mouse and human TATA-factors (TFIID)

1991 • 84 citations

The mouse CREB (cAMP responsive element binding protein) gene: Structure, promoter analysis, and chromosomal localization

1992 • 37 citations

Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene

1995 • 18 citations