A role for Th17 cells in the regulation of tertiary lymphoid follicles

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

2006 • 4,815 citations

IL-17 and Th17 Cells

2009 • 4,491 citations

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 • 3,545 citations

IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages

2007 • 1,809 citations

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

2006 • 1,806 citations

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

2008 • 1,801 citations

Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

2007 • 1,773 citations

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

2008 • 1,695 citations

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

2011 • 1,640 citations

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

2008 • 1,624 citations

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

2008 • 1,544 citations

TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology

2007 • 1,448 citations

Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology

2006 • 1,321 citations

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

2010 • 1,304 citations

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

2008 • 1,188 citations

Detection of Ectopic B‐cell Follicles with Germinal Centers in the Meninges of Patients with Secondary Progressive Multiple Sclerosis

2004 • 1,146 citations

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

2007 • 1,135 citations

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

2009 • 1,120 citations

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

2008 • 1,014 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

1999 • 943 citations

An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

2003 • 917 citations

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

2007 • 870 citations

Development of peripheral lymphoid organs and natural killer cells depends on the helix–loop–helix inhibitor Id2

1999 • 841 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

1998 • 810 citations

Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity

2004 • 742 citations

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

2008 • 740 citations

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

2011 • 739 citations

Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles

2011 • 727 citations

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

2009 • 723 citations

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

2008 • 715 citations

Requirement for RORγ in Thymocyte Survival and Lymphoid Organ Development

2000 • 714 citations

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

2011 • 696 citations

Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain

2007 • 690 citations

Lymphoid Neogenesis in Rheumatoid Synovitis

2001 • 656 citations

T1 /podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

2003 • 640 citations

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

2008 • 629 citations

Up-Regulation of the Lymphatic Marker Podoplanin, a Mucin-Type Transmembrane Glycoprotein, in Human Squamous Cell Carcinomas and Germ Cell Tumors

2005 • 598 citations

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut

2010 • 552 citations

New insights into the development of lymphoid tissues

2010 • 537 citations

T Cell Activation in Rheumatoid Synovium Is B Cell Dependent

2001 • 521 citations

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

2008 • 486 citations

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

2009 • 449 citations

Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis.

1996 • 433 citations

Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

2011 • 426 citations

NETWORK COMMUNICATIONS: Lymphotoxins, LIGHT, and TNF

2004 • 424 citations

Increased interleukin-17 production in patients with systemic sclerosis

2000 • 391 citations

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

2011 • 390 citations

IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways

2004 • 372 citations

Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium

2010 • 349 citations

Interleukin‐17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

2008 • 324 citations

Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis

2004 • 310 citations

In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis

2010 • 309 citations

Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis

2000 • 308 citations

Lymphotoxin/LIGHT, lymphoid microenvironments and autoimmune disease

2003 • 291 citations

Lymphoid Chemokine B Cell-Attracting Chemokine-1 (CXCL13) Is Expressed in Germinal Center of Ectopic Lymphoid Follicles Within the Synovium of Chronic Arthritis Patients

2001 • 277 citations

An immunohistological analysis of lymphocyte subpopulations and their microenvironment in the synovial membranes of patients with rheumatoid arthritis using monoclonal antibodies.

1982 • 273 citations

Ectopic lymphoid tissues and local immunity

2008 • 260 citations

Interleukin-17 enhances tumor necrosis factor ?-induced synthesis of interleukins 1, 6, and 8 in skin and synovial fibroblasts: A possible role as a ?fine-tuning cytokine? in inflammation processes

2001 • 246 citations

Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis

2007 • 245 citations

Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis

2005 • 240 citations

Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid‐like structures in Sjögren's syndrome

2005 • 239 citations

Ectopic Germinal Center Formation in Rheumatoid Synovitis

2003 • 233 citations

Secondary Lymphoid Organs: Responding to Genetic and Environmental Cues in Ontogeny and the Immune Response

2009 • 232 citations

Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells

2012 • 218 citations

Human Th17 Cells Share Major Trafficking Receptors with Both Polarized Effector T Cells and FOXP3+ Regulatory T Cells

2008 • 218 citations

TH-17 cells in rheumatoid arthritis

2008 • 212 citations

Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

2002 • 202 citations

Ectopic Lymphoid-Organ Development Occurs through Interleukin 7-Mediated Enhanced Survival of Lymphoid-Tissue-Inducer Cells

2007 • 197 citations

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells

2011 • 184 citations

CD8 T Cells Are Required for the Formation of Ectopic Germinal Centers in Rheumatoid Synovitis

2002 • 181 citations

Properties and origin of human Th17 cells

2009 • 176 citations

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

2009 • 166 citations

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium

2011 • 154 citations

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease

2010 • 136 citations

Lymphoid organ development and cell migration

2003 • 135 citations

Increased serum interleukin 17 in patients with systemic lupus erythematosus

2009 • 135 citations

Analysis and classification of B-cell infiltrates in lupus and ANCA-associated nephritis

2008 • 122 citations

IL-17 in Systemic Lupus Erythematosus

2010 • 108 citations

Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting

2003 • 100 citations

The gene expression of type 17 T-helper cell-related cytokines in the urinary sediment of patients with systemic lupus erythematosus

2009 • 93 citations

Human Th17 cells in infection and autoimmunity

2009 • 88 citations

TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes.

1999 • 77 citations

TNF and Lymphotoxin β Cooperate in the Maintenance of Secondary Lymphoid Tissue Microarchitecture But Not in the Development of Lymph Nodes

1999 • 65 citations

B-cell differentiation in the CNS of patients with multiple sclerosis

2005 • 64 citations

Intestinal Cryptopatch Formation in Mice Requires Lymphotoxin α and the Lymphotoxin β Receptor

2004 • 63 citations

Type17 T-cells in Central Nervous System Autoimmunity and Tumors

2012 • 27 citations

Lymphoid Organogenesis in the Intestine

2005 • 23 citations

In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease

2012 • 20 citations

Induction of Intestinal Lymphoid Tissue

2006 • 13 citations

Rorγt+ Innate Lymphoid Cells in Intestinal Homeostasis and Immunity

2011 • 11 citations