Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

2006 • 6,720 citations

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

2006 • 4,815 citations

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 • 4,529 citations

IL-17 and Th17 Cells

2009 • 4,491 citations

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 • 3,545 citations

Transforming growth factor-β induces development of the TH17 lineage

2006 • 3,014 citations

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

2006 • 2,234 citations

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

2006 • 1,806 citations

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

2008 • 1,801 citations

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

2008 • 1,695 citations

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

2008 • 1,624 citations

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

2008 • 1,544 citations

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

2008 • 1,524 citations

Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense

2001 • 1,505 citations

TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology

2007 • 1,448 citations

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

2007 • 1,446 citations

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

2010 • 1,304 citations

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

2008 • 1,139 citations

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

2008 • 1,131 citations

I<scp>nterleukin</scp>-10<scp>and</scp>R<scp>elated</scp>C<scp>ytokines and</scp>R<scp>eceptors</scp>

2004 • 1,063 citations

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

2009 • 1,038 citations

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

2009 • 981 citations

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways

2008 • 750 citations

The Proto-Oncogene c-maf Is Responsible for Tissue-Specific Expression of Interleukin-4

1996 • 677 citations

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

2010 • 674 citations

Interleukin-22 but Not Interleukin-17 Provides Protection to Hepatocytes during Acute Liver Inflammation

2007 • 617 citations

The AP-1 transcription factor Batf controls TH17 differentiation

2009 • 568 citations

Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity

2009 • 566 citations

Cloning and Characterization of IL-10-Related T Cell-Derived Inducible Factor (IL-TIF), a Novel Cytokine Structurally Related to IL-10 and Inducible by IL-9

2000 • 497 citations

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

2008 • 486 citations

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

2009 • 456 citations

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun.

1994 • 418 citations

The Transcription Factor c-Maf Controls the Production of Interleukin-4 but Not Other Th2 Cytokines

1999 • 377 citations

Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A

2010 • 360 citations

Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1α, and TNF-α Recapitulates Some Features of Psoriasis

2010 • 305 citations

Interleukin-22-Producing Natural Killer Cells and Lymphoid Tissue Inducer-like Cells in Mucosal Immunity

2009 • 296 citations

The Protooncogene c-Maf Is an Essential Transcription Factor for IL-10 Gene Expression in Macrophages

2005 • 239 citations

c-Maf Regulates IL-10 Expression during Th17 Polarization

2009 • 217 citations

Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

2008 • 215 citations

IL-22 ⁺ CD4 ⁺ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

2010 • 191 citations

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun

1994 • 133 citations

c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4+ T cells

2009 • 120 citations

IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues

2004 • 118 citations

Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease

2010 • 110 citations

IL-6 Plays a Unique Role in Initiating c-Maf Expression during Early Stage of CD4 T Cell Activation

2005 • 108 citations

c-Maf Interacts with c-Myb To Regulate Transcription of an Early Myeloid Gene during Differentiation

1998 • 90 citations

Large Maf Transcription Factors: Cousins of AP-1 Proteins and Important Regulators of Cellular Differentiation

2016 • 82 citations

c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction

2002 • 76 citations

siRNA stabilization prolongs gene knockdown in primary T lymphocytes

2008 • 75 citations

Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency

2004 • 66 citations

Transcriptional Regulation of Mouse αB- and γF-Crystallin Genes in Lens: Opposite Promoter-specific Interactions Between Pax6 and Large Maf Transcription Factors

2004 • 64 citations

Maf Transcriptionally Activates the Mouse p53Promoter and Causes a p53-dependent Cell Death

2000 • 49 citations