A Crucial Role for Tryptophan Catabolism at the Host/Candida albicansInterface

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

1998 • 2,538 citations

Ido expression by dendritic cells: tolerance and tryptophan catabolism

2004 • 2,235 citations

Immunity to fungal infections

2011 • 1,737 citations

Modulation of tryptophan catabolism by regulatory T cells

2003 • 1,323 citations

CTLA-4–Ig regulates tryptophan catabolism in vivo

2002 • 1,150 citations

Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase

2002 • 1,035 citations

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

T cell apoptosis by tryptophan catabolism

2002 • 960 citations

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan.

1984 • 847 citations

Tolerance, DCs and tryptophan: much ado about IDO

2003 • 752 citations

Immunity to fungal infections

2003 • 731 citations

Tryptophan and the immune response

2003 • 725 citations

Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

1999 • 650 citations

The Contribution of the Toll-Like/IL-1 Receptor Superfamily to Innate and Adaptive Immunity to Fungal Pathogens In Vivo

2004 • 500 citations

Dendritic Cells Discriminate between Yeasts and Hyphae of the Fungus Candida albicans

2000 • 498 citations

Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro.

1993 • 471 citations

Ligation of B7-1/B7-2 by Human CD4+ T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells

2004 • 459 citations

Simultaneous Measurement of Serum Tryptophan and Kynurenine by HPLC,

1997 • 410 citations

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86

2004 • 296 citations

B7/CD28-Dependent CD4+CD25+ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans

2002 • 236 citations

Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice

2003 • 226 citations

Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-γ-independent mechanism

2001 • 206 citations

Immunity to Candida albicans: Th1, Th2 cells and beyond

1999 • 195 citations

Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance

1991 • 195 citations

The role of IFN-γ in the outcome of chlamydial infection

2002 • 188 citations

Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria.

1998 • 175 citations

Expression of Indoleamine 2,3-Dioxygenase, Tryptophan Degradation, and Kynurenine Formation during In Vivo Infection withToxoplasma gondii: Induction by Endogenous Gamma Interferon and Requirement of Interferon Regulatory Factor 1

2002 • 169 citations

Endogenous Interleukin 4 Is Required for Development of Protective CD4+ T Helper Type 1 Cell Responses to Candida albicans

1998 • 159 citations

Candida mannan: chemistry, suppression of cell-mediated immunity, and possible mechanisms of action

1991 • 159 citations

Aerobic and anaerobic NAD⁺ metabolism in Saccharomyces cerevisiae

2002 • 152 citations

T Helper Cell Type 1 (Th1)- and Th2-like Responses Are Present in Mice with Gastric Candidiasis but Protective Immunity Is Associated with Th1 Development

1995 • 139 citations

Fungi, dendritic cells and receptors: a host perspective of fungal virulence

2002 • 139 citations

CD80+Gr-1+ Myeloid Cells Inhibit Development of Antifungal Th1 Immunity in Mice with Candidiasis

2002 • 138 citations

A TH1-TH2-like switch in candidiasis: new perspectives for therapy

1995 • 133 citations

Adaptation of Candida albicans to the host environment: the role of morphogenesis in virulence and survival in mammalian hosts

2003 • 128 citations

Normal and Deficient Neutrophils Can Cooperate to Damage Aspergillus fumigatus Hyphae

1990 • 127 citations

Specific inhibition of in vitro Candida-induced lymphocyte proliferation by polysaccharidic antigens present in the serum of patients with chronic mucocutaneous candidiasis.

1978 • 124 citations

Ifn-γ Activated Indoleamine 2,3-Dioxygenase Activity in Human Cells is an Antiparasitic and an Antibacterial Effector Mechanism

1999 • 115 citations

Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: Implications for inflammatory bowel diseases

2002 • 110 citations

Characteristics of Invasive Candidiasis in Gamma Interferon- and Interleukin-4-Deficient Mice: Role of Macrophages in Host Defense againstCandida albicans

1998 • 103 citations

IFN-γ Inhibits Presentation of a Tumor/Self Peptide by CD8α− Dendritic Cells Via Potentiation of the CD8α+ Subset

2000 • 101 citations

The exploitation of distinct recognition receptors in dendritic cells determines the full range of host immune relationships with Candida albicans

2003 • 100 citations

Candidiasis in Interferon- Knockout (IFN- -/-) Mice

1998 • 97 citations

Rapid identification of yeast species using three primers in a polymerase chain reaction.

1993 • 96 citations

Prostaglandin E2 enhances and gamma interferon inhibits germ tube formation in Candida albicans

1990 • 94 citations

TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.

1995 • 93 citations

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.

1996 • 89 citations

Interferon‐γ‐Induced Activation of Indoleamine 2,3‐Dioxygenase in Cord Blood Monocyte‐Derived Macrophages Inhibits the Growth of Group B Streptococci

1998 • 88 citations

Interleukin‐12 but not interferon‐γ production correlates with induction of T helper type‐1 phenotype in murine candidiasis

1994 • 85 citations

Deregulated Production of Protective Cytokines in Response toCandida albicansInfection in Patients with Chronic Mucocutaneous Candidiasis

2003 • 78 citations

IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection.

1998 • 77 citations

Enhancement of Innate Immunity againstMycobacterium aviumInfection by Immunostimulatory DNA Is Mediated by Indoleamine 2,3-Dioxygenase

2001 • 74 citations

IL-10 Is Required for Development of Protective Th1 Responses in IL-12-Deficient Mice uponCandida albicansInfection

1998 • 73 citations

The role of recombinant murine IL-12 and IFN-gamma in the pathogenesis of a murine systemic Candida albicans infection.

1998 • 67 citations

IFN-γ Is Required for IL-12 Responsiveness in Mice withCandida albicansInfection

1998 • 62 citations

The Role of Recombinant Murine IL-12 and IFN-γ in the Pathogenesis of a Murine Systemic Candida albicans Infection

1998 • 57 citations

The yeast gene YJR025c encodes a 3‐hydroxyanthranilic acid dioxygenase and is involved in nicotinic acid biosynthesis

1998 • 53 citations

Protective effect of picolinic acid on mice intracerebrally infected with lethal doses of Candida albicans

1993 • 30 citations

The control of morphogenesis in Saccharomyces cerevisiae by Elm1 kinase is responsive to RAS/cAMP pathway activity and tryptophan availability

1997 • 21 citations