Adaptation of Candida albicans to the host environment: the role of morphogenesis in virulence and survival in mammalian hosts

Toll Pathway-Dependent Blockade of CD4 ⁺ CD25 ⁺ T Cell-Mediated Suppression by Dendritic Cells

2003 • 2,023 citations

CTLA-4–Ig regulates tryptophan catabolism in vivo

2002 • 1,150 citations

The Plasticity of Dendritic Cell Responses to Pathogens and Their Components

2001 • 760 citations

The glyoxylate cycle is required for fungal virulence

2001 • 714 citations

Pseudomonas - Candida Interactions: An Ecological Role for Virulence Factors

2002 • 569 citations

White-Opaque Switching in Candida albicans Is Controlled by Mating-Type Locus Homeodomain Proteins and Allows Efficient Mating

2002 • 557 citations

Dendritic Cells Discriminate between Yeasts and Hyphae of the Fungus Candida albicans

2000 • 498 citations

The Role of Toll‐like Receptor (TLR) 2 and TLR4 in the Host Defense against Disseminated Candidiasis

2002 • 478 citations

Fungal morphogenesis and host invasion

2002 • 470 citations

The C‐type lectin DC‐SIGN (CD209) is an antigen‐uptake receptor for Candida albicans on dendritic cells

2003 • 365 citations

Transcription Profiling ofCandida albicansCells Undergoing the Yeast-to-Hyphal Transition

2002 • 364 citations

Signaling through Adenylyl Cyclase Is Essential for Hyphal Growth and Virulence in the Pathogenic FungusCandida albicans

2001 • 340 citations

Challenging the trade-off model for the evolution of virulence: is virulence management feasible?

2003 • 329 citations

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans.

1996 • 319 citations

Saccharomyces cerevisiae‐ and Candida albicans‐Derived Mannan Induced Production of Tumor Necrosis Factor Alpha by Human Monocytes in a CD14‐ and Toll‐Like Receptor 4‐Dependent Manner

2002 • 291 citations

Metabolic specialization associated with phenotypic switching inCandidaalbicans

2002 • 271 citations

Candida albicans Hyphal Formation and the Expression of the Efg1-Regulated Proteinases Sap4 to Sap6 Are Required for the Invasion of Parenchymal Organs

2002 • 251 citations

B7/CD28-Dependent CD4+CD25+ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans

2002 • 236 citations

DNA Array Studies Demonstrate Convergent Regulation of Virulence Factors by Cph1, Cph2, and Efg1 in Candida albicans

2001 • 218 citations

Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway

2002 • 218 citations

Cytokine and Chemokine Production by Human Oral and Vaginal Epithelial Cells in Response toCandida albicans

2002 • 165 citations

Candida commensalism and virulence: the evolution of phenotypic plasticity

2002 • 159 citations

Production of Prostaglandins and Leukotrienes by Pathogenic Fungi

2002 • 149 citations

Candida albicansIs Phagocytosed, Killed, and Processed for Antigen Presentation by Human Dendritic Cells

2001 • 145 citations

Complement Is Essential for Protection by an IgM and an IgG3 Monoclonal Antibody Against Experimental, Hematogenously Disseminated Candidiasis

2001 • 142 citations

Fungi, dendritic cells and receptors: a host perspective of fungal virulence

2002 • 139 citations

CD80+Gr-1+ Myeloid Cells Inhibit Development of Antifungal Th1 Immunity in Mice with Candidiasis

2002 • 138 citations

Interactions of fungi with phagocytes

2002 • 127 citations

Dendritic Cells Pulsed with Fungal RNA Induce Protective Immunity toCandida albicansin Hematopoietic Transplantation

2002 • 122 citations

Linking fungal morphogenesis with virulence

2002 • 116 citations

New perspectives on the immunology of chronic mucocutaneous candidiasis

2002 • 115 citations

Disruption of the Candida albicans TPS2 Gene Encoding Trehalose-6-Phosphate Phosphatase Decreases Infectivity without Affecting Hypha Formation

2002 • 112 citations

A Saccharomyces cerevisiae mutant with increased virulence

2003 • 102 citations

Fungal Pathogenesis: Principles and Clinical Applications

2001 • 90 citations

Candida albicansKilling by RAW 264.7 Mouse Macrophage Cells: Effects ofCandidaGenotype, Infection Ratios, and Gamma Interferon Treatment

2002 • 88 citations

Rapid recruitment of late endosomes and lysosomes in mouse macrophages ingesting Candida albicans

1999 • 87 citations

A role for antibodies in the generation of memory antifungal immunity

2003 • 85 citations

Candida albicans Phospholipomannan Promotes Survival of Phagocytosed Yeasts through Modulation of Bad Phosphorylation and Macrophage Apoptosis

2003 • 80 citations

Complete glycosylphosphatidylinositol anchors are required in Candida albicans for full morphogenesis, virulence and resistance to macrophages

2002 • 79 citations

Differential chemokine response of human monocytes to yeast and hyphal forms of Candida albicans and its relation to the beta-1,6 glucan of the fungal cell wall.

2000 • 77 citations

Comparative virulence of Candida albicans yeast and filamentous forms in orally and intravenously inoculated mice

2003 • 68 citations

Temporal Expression of the Candida albicans Genes CHK1 and CSSK1 , Adherence, and Morphogenesis in a Model of Reconstituted Human Esophageal Epithelial Candidiasis

2002 • 55 citations

Differential chemokine response of human monocytes to yeast and hyphal forms ofCandida albicansand its relation to the β-1,6 glucan of the fungal cell wall

2000 • 54 citations

Differential secretion of Sap4–6 proteins in Candida albicans during hyphae formation

2002 • 53 citations

Spt3 Plays Opposite Roles in Filamentous Growth in Saccharomyces cerevisiae and Candida albicans and Is Required for C. albicans Virulence

2002 • 48 citations

The Interaction of Fungi with Dendritic Cells: Implications for Th Immunity and Vaccination

2002 • 44 citations

Genomic approaches to fungal pathogenicity

2002 • 40 citations

Cytokines and Chemokines in Infectious Diseases Handbook

2003 • 40 citations

Defective Induction of Interleukin-12 in Human Monocytes by Germ-Tube Forms ofCandida albicans

2000 • 38 citations

Downregulation of IFN-γ production in patients with recurrent vaginal candidiasis

2002 • 36 citations

Lymphocyte Adhesion toCandida albicans

2002 • 34 citations

Candida albicansStimulates Local Expression of Leukocyte Adhesion Molecules and Cytokines In Vivo

2002 • 30 citations

Hyphae and Yeasts ofCandida albicansDifferentially Regulate Interleukin-12 Production by Human Blood Monocytes: Inhibitory Role ofC. albicansGermination

2001 • 28 citations

Cytokines of Innate and Adaptive Immunity to Candida albicans

2003 • 6 citations