Role of B7-H1 and B7-H4 molecules in down-regulating effector phase of T-cell immunity: novel cancer escaping mechanisms

Cancer immunoediting: from immunosurveillance to tumor escape

2002 • 4,911 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

2000 • 4,853 citations

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

2002 • 4,625 citations

Cancer immunotherapy: moving beyond current vaccines

2004 • 2,932 citations

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

2002 • 2,879 citations

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

1999 • 2,574 citations

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

1999 • 2,380 citations

Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice

2001 • 1,761 citations

Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

1996 • 1,473 citations

Progress in human tumour immunology and immunotherapy

2001 • 1,327 citations

Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

2003 • 1,255 citations

Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity

2004 • 1,213 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity

2005 • 972 citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 • 886 citations

PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells

2004 • 748 citations

B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity

2003 • 665 citations

B7-H1 Expression on Non-Small Cell Lung Cancer Cells and Its Relationship with Tumor-Infiltrating Lymphocytes and Their PD-1 Expression

2004 • 664 citations

B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma.

2003 • 481 citations

B7S1, a Novel B7 Family Member that Negatively Regulates T Cell Activation

2003 • 407 citations

B7x: A widely expressed B7 family member that inhibits T cell activation

2003 • 380 citations

B7-H1 Determines Accumulation and Deletion of Intrahepatic CD8+ T Lymphocytes

2004 • 375 citations

PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver

2003 • 373 citations

Spinning molecular immunology into successful immunotherapy

2002 • 364 citations

Immune defects observed in patients with primary malignant brain tumors

1999 • 319 citations

B7-H1 pathway and its role in the evasion of tumor immunity

2003 • 272 citations

Genomic Organization and Expression Analysis of B7-H4, an Immune Inhibitory Molecule of the B7 Family

2003 • 238 citations

Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis

2003 • 185 citations

Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer

1996 • 178 citations

Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

2003 • 168 citations

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

2002 • 155 citations

Tumor Immunology

1998 • 146 citations

Loss of HLA-A,B,C allele products and lymphocyte function-associated antigen 3 in colorectal neoplasia.

1989 • 119 citations

Multiple regulatory pathways of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in tumors

2004 • 94 citations

Immunological ignorance of silent antigens as an explanation of tumor evasion

1998 • 93 citations

The paradox of T cell?mediated antitumor immunity in spite of poor clinical outcome in human melanoma

2004 • 70 citations

Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation

2003 • 56 citations

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin 10 secretion

2000 • 54 citations

Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis

2003 • 17 citations

Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer

1996 • 11 citations