Regulation of two rat serine‐protease inhibitor gene promoters by somatotropin and glucocorticoids

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

1989 • 614 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally

1990 • 410 citations

Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters.

1988 • 323 citations

Accelerated evolution in the reactive centre regions of serine protease inhibitors

1987 • 293 citations

Higher plant phosphoenolpyruvate carboxylase

1987 • 218 citations

Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer.

1991 • 206 citations

Structural Determinants of a Glucocorticoid Receptor Recognition Element

1990 • 201 citations

The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

1991 • 188 citations

The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation.

1991 • 163 citations

Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats

1992 • 139 citations

Ultrastructural and biochemical studies of isolated adult rat hepatocytes prepared under hypoxic conditions Cryopreservation of hepatocytes

1976 • 112 citations

An inducible nuclear factor binds to a growth hormone-regulated gene.

1990 • 109 citations

A highly sensitive, mixed-phase assay for chloramphenicol acetyltransferase activity in transfected cells

1989 • 101 citations

Growth hormone induces two mRNA species of the serine protease inhibitor gene family in rat liver.

1987 • 97 citations

Estrogen-Dependent in Vitro Transcription from the Vitellogenin Promoter in Liver Nuclear Extracts

1988 • 78 citations

A nuclear factor I-like activity and a liver-specific repressor govern estrogen-regulated in vitro transcription from the Xenopus laevis vitellogenin B1 promoter.

1989 • 65 citations

Analysis by cell-free transcription of the liver-specific pyruvate kinase gene promoter.

1989 • 61 citations

T-Kininogen Gene Expression Is Induced during Aging

1989 • 60 citations

Study of a growth hormone-regulated protein secreted by rat hepatocytes: cDNA cloning, anti-protease activity and regulation of its synthesis by various hormones.

1987 • 56 citations

Delayed secondary glucocorticoid response elements. Unusual nucleotide motifs specify glucocorticoid receptor binding to transcribed regions of alpha 2u-globulin DNA.

1991 • 53 citations

Molecular characterization of three rat liver serine‐protease inhibitors affected by inflammation and hypophysectomy

1990 • 53 citations

The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones.

1987 • 52 citations

T-kininogen gene expression is induced during aging.

1989 • 51 citations

Hypophysectomy and Growth Hormone Receptors in Liver Membranes of Male Rats

1984 • 49 citations

Hormonal Regulation of Growth Hormone Receptors in Primary Cultured Rat Hepatocytes

1990 • 38 citations

Analysis of proteins binding to the proximal promoter region of two rat serine protease inhibitor genes

1992 • 31 citations

Multipartite structure of a negative regulatory element associated with a steroid hormone-inducible promoter.

1991 • 31 citations

The analysis of the human hemopexin promoter defines a new class of liver-specific genes.

1989 • 30 citations

Electroporation-mediated gene transfer into hepatocytes: Preservation of a growth hormone response

1992 • 29 citations

Primary structure and assignment to chromosome 6 of three related rat genes encoding liver serine protease inhibitors

1990 • 26 citations

Multiple protein binding sites within the ovalbumin gene 5′-flanking region: isolation and characterization of sequence-specific binding proteins

1989 • 18 citations

Synthesis of the growth hormone‐regulated rat liver anti‐protease GHR‐P⁶³ is inhibited by acute inflammation

1987 • 9 citations