Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism.

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

1992 • 953 citations

Human gene therapy comes of age

1992 • 927 citations

A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

1988 • 606 citations

A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes

1976 • 417 citations

The Family of Glycogen Phosphorylases: Structure and Functio

1989 • 386 citations

Evaluation of the Transfer and Expression in Mice of an Enzyme-Encoding Gene Using a Human Adenovirus Vector

1990 • 325 citations

Glycogen phosphorylase: control by phosphorylation and allosteric effectors

1992 • 316 citations

High-Resolution Chromosome Sorting and DNA Spot-Blot Analysis Assign McArdle's Syndrome to Chromosome 11

1984 • 240 citations

Eukaryotic viral vectors

1982 • 177 citations

Infection of eucaryotic cells by helper-independent recombinant adenoviruses: early region 1 is not obligatory for integration of viral DNA

1984 • 170 citations

Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen.

1988 • 155 citations

Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes.

1988 • 136 citations

Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes.

1990 • 128 citations

Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage.

1986 • 116 citations

Phosphorylase: a biological transducer

1992 • 109 citations

Regulation of beta-cell glucose transporter gene expression.

1990 • 107 citations

Evidence for Suppression of Hepatic Glucose-6-Phosphatase with Carbohydrate Feeding

1984 • 104 citations

The Relation of Phosphorylase to Glycogenolysis in Skeletal Muscle and Heart of Mice

1963 • 102 citations

Intron/exon structure of the human gene for the muscle isozyme of glycogen phosphorylase

1987 • 78 citations

Complete cDNA sequence for rabbit muscle glycogen phosphorylase

1986 • 73 citations

The inhibition of glycogen phosphorylase by uridine diphosphate glucose

1961 • 63 citations

Glycogen phosphorylase structures and function

1982 • 62 citations

Subunit phosphorylation and activation of skeletal muscle phosphorylase kinase by the cAMP-dependent protein kinase. Divalent metal ion, ATP, and protein concentration dependence.

1985 • 51 citations

The polymorphic locus for glycogen storage disease VI (liver glycogen phosphorylase) maps to chromosome 14.

1987 • 48 citations

Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively

1989 • 45 citations

Human liver glycogen phosphorylase. Kinetic properties and assay in biopsy specimens

1976 • 39 citations

Insulin counteraction of α-adrenergic effects on liver glycogen metabolism

1978 • 36 citations

Skeletal muscle phosphorylase kinase deficiency: Detection of a protein lacking any activity in ICR/IAn mice

1973 • 35 citations

Reconstitution of enzymatic activity in hepatocytes of phenylalanine hydroxylase-deficient mice

1992 • 34 citations

Anti-insulin effects of amylin and calcitonin-gene-related peptide on hepatic glycogen metabolism

1991 • 34 citations

An engineered liver glycogen phosphorylase with AMP allosteric activation

1991 • 32 citations

Role of AMP on the activation of glycogen synthase and phosphorylase by adenosine, fructose, and glutamine in rat hepatocytes.

1990 • 32 citations

Cellular Engineering for the Treatment of Metabolic Disorders: Prospects for Therapy in Diabetes

1992 • 31 citations

Clinical application of somatic gene therapy in inborn errors of metabolism

1990 • 26 citations

A comparison of the activator sites of liver and muscle glycogen phosphorylase b.

1982 • 23 citations

The hepatic glycogenolysis induced by reversible ischaemia or KCN is exclusively catalysed by phosphorylase a

1988 • 23 citations

Rabbit liver phosphorylase: Improvement of the purification procedure and assay of the inactive b form

1982 • 22 citations

Activation of hepatocyte glycogen synthase by metabolic inhibitors

1986 • 15 citations

The Glycogen Storage Disease (gsd/gsd) Rat

1988 • 12 citations

Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation

1991 • 11 citations