Lysosomal degradation of ribonuclease A and ribonuclease S-protein microinjected into the cytosol of human fibroblasts.

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells: Part 2

1976 • 1,060 citations

Mechanisms of Intracellular Protein Breakdown

1982 • 647 citations

A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes.

1977 • 553 citations

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1984 • 533 citations

24 Bovine Pancreatic Ribonuclease

1971 • 437 citations

Two species of lysosomal organelles in cultured human fibroblasts

1979 • 360 citations

Ammonia inhibits phagosome–lysosome fusion in macrophages

1980 • 339 citations

Protein Turnover and Lysosome Function

1978 • 279 citations

Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling

1980 • 252 citations

The Molecular Weights of Vertebrate Histones Exploiting a Modified Sodium Dodecyl Sulfate Electrophoretic Method

1971 • 251 citations

Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells

1976 • 234 citations

The ubiquitin‐mediated proteolytic pathway and mechanisms of energy‐dependent intracellular protein degradation

1984 • 221 citations

The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts.

1983 • 196 citations

12 Pancreatic Ribonuclease

1982 • 178 citations

Studies on the Correlation between Size and Relative Degradation Rate of Soluble Proteins

1973 • 165 citations

The Dynamic State of Body Constituents

1942 • 158 citations

The effect of protease inhibitors and decreased temperature on the degradation of different classes of proteins in cultured hepatocytes

1979 • 157 citations

Amino acid control of autophagic sequestration and protein degradation in isolated rat hepatocytes.

1984 • 150 citations

Inhibition of proteolytic activity of calcium activated neutral protease by leupeptin and antipain

1978 • 130 citations

Sequestration of cytoplasmic enzymes in an autophagic vacuole-lysosomal system induced by injection of leupeptin.

1983 • 128 citations

Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells.

1982 • 128 citations

Altered degradation of proteins microinjected into senescent human fibroblasts.

1982 • 122 citations

Degradation of proteins microinjected into IMR-90 human diploid fibroblasts.

1981 • 121 citations

Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis.

1982 • 118 citations

Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine.

1984 • 114 citations

Minireview: Mechanisms of protein turnover in cultured cells

1981 • 104 citations

The selective degradation of injected proteins occurs principally in the cytosol rather than in lysosomes

1981 • 103 citations

Effect of chloroquine on the internalization of 125I-insulin into subcellular fractions of rat liver. Evidence for an effect of chloroquine on Golgi elements.

1982 • 102 citations

Mechanisms of Cellular Protein Catabolism

2009 • 100 citations

Regulation of intracellular protein degradation in IMR‐90 human diploid fibroblasts

1983 • 99 citations

Regulation of catabolism of microinjected ribonuclease A requires the amino-terminal 20 amino acids.

1983 • 81 citations

Endoplasmic reticulum and autophagy in rat hepatocytes.

1978 • 69 citations

Enzyme inactivation via disulphide–thiol exchange as catalysed by a rat liver membrane protein

1980 • 61 citations

Turnover of Acetylcholine Receptors in Skeletal Muscle

1982 • 52 citations

Autophagy of metabolically inert substances injected into fibroblasts in culture

1981 • 47 citations

[3H]Raffinose, a novel radioactive label for determining organ sites of catabolism of proteins in the circulation.

1979 • 45 citations

In vitro uptake of particles by lysosomes

1980 • 44 citations

Intracellular protein degradation: Basis of a self-regulating mechanism for the proteolysis of endogenous proteins

1984 • 40 citations

Lysosomes and membrane recycling. A hypothesis

1977 • 36 citations

Microinjection of cultured cells using red-cell-mediated fusion and osmotic lysis of pinosomes: A review of methods and applications

1984 • 35 citations

Targeting of beta-glucuronidase to lysosomes in mannose 6-phosphate receptor-deficient MOPC 315 cells.

1984 • 33 citations

The regulation of proteolysis in normal fibroblasts as they approach confluence. Evidence for the participation of the lysosomal system

1982 • 28 citations

Swainsonine inhibits glycoprotein degradation by isolated rat liver lysosomes.

1984 • 23 citations

Erythrocyte-mediated microinjection, a technique to study protein degradation in muscle cells

1983 • 21 citations

Albumin in Chicken Skeletal Muscle

1982 • 19 citations

Cytoplasmic proteases of rat liver parenchymal cells

1982 • 12 citations

Metabolic alterations and distribution of rat liver lysosomes in colloidal silica

1983 • 11 citations

Purification and properties of three cytosolic ribonucleases of mouse liver

1984 • 9 citations

Mechanism and regulation of protein turnover in higher animals

1982 • 5 citations