Developmental Decrease in NMDA Receptor Desensitization Associated with Shift to Synapse and Interaction with Postsynaptic Density-95

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

Glutamate receptor ion channels

2005 • 3,667 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

1995 • 1,861 citations

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

2002 • 1,612 citations

Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.

2006 • 1,287 citations

PSD-95 Involvement in Maturation of Excitatory Synapses

2000 • 1,238 citations

N-methyl-D-aspartic acid receptor structure and function

1994 • 989 citations

Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions

2002 • 964 citations

Specific Coupling of NMDA Receptor Activation to Nitric Oxide Neurotoxicity by PSD-95 Protein

1999 • 821 citations

The Incorporation of NMDA Receptors with a Distinct Subunit Composition at Nascent Hippocampal SynapsesIn Vitro

1999 • 780 citations

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases

1996 • 735 citations

Activity-Dependent Decrease in NMDA Receptor Responses During Development of the Visual Cortex

1992 • 731 citations

High-Affinity Zinc Inhibition of NMDA NR1–NR2A Receptors

1997 • 629 citations

NR2A Subunit Expression Shortens NMDA Receptor Synaptic Currents in Developing Neocortex

1997 • 612 citations

Excitatory and inhibitory autaptic currents in isolated hippocampal neurons maintained in cell culture.

1991 • 589 citations

Role of Actin in Anchoring Postsynaptic Receptors in Cultured Hippocampal Neurons: Differential Attachment of NMDA versus AMPA Receptors

1998 • 557 citations

Synaptic Strength Regulated by Palmitate Cycling on PSD-95

2002 • 547 citations

Heteromultimerization and NMDA Receptor-Clustering Activity of Chapsyn-110, a Member of the PSD-95 Family of Proteins

1996 • 539 citations

Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse

1992 • 529 citations

Subunit-Specific NMDA Receptor Trafficking to Synapses

2002 • 503 citations

Regulation of NMDA Receptors by an Associated Phosphatase-Kinase Signaling Complex

1999 • 497 citations

Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase

1994 • 483 citations

The impact of receptor desensitization on fast synaptic transmission

1996 • 478 citations

Targeting of PKA to Glutamate Receptors through a MAGUK-AKAP Complex

2000 • 463 citations

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro

1993 • 447 citations

Synaptic Desensitization of NMDA Receptors by Calcineurin

1995 • 404 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

1993 • 394 citations

Enlightening the Postsynaptic Density

1997 • 381 citations

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N -methyl- <scp>d</scp> -aspartate receptor subunit NR2A

1999 • 369 citations

Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons

1998 • 364 citations

Ligand-Gated Ion Channel Interactions with Cytoskeletal and Signaling Proteins

2000 • 352 citations

Synaptic Targeting of the Postsynaptic Density Protein PSD-95 Mediated by Lipid and Protein Motifs

1999 • 327 citations

Yotiao, a Novel Protein of Neuromuscular Junction and Brain That Interacts with Specific Splice Variants of NMDA Receptor Subunit NR1

1998 • 301 citations

β-Adrenergic Regulation of Synaptic NMDA Receptors by cAMP-Dependent Protein Kinase

1996 • 280 citations

The Actin-Severing Protein Gelsolin Modulates Calcium Channel and NMDA Receptor Activities and Vulnerability to Excitotoxicity in Hippocampal Neurons

1997 • 269 citations

Subtype-Dependence of NMDA Receptor Channel Open Probability

1999 • 259 citations

Activation and desensitization of N‐methyl‐D‐aspartate receptors in nucleated outside‐out patches from mouse neurones.

1992 • 240 citations

Distinct Roles of Synaptic and Extrasynaptic NMDA Receptors in Excitotoxicity

2000 • 238 citations

Differential Sensitivity of RecombinantN-Methyl-d-Aspartate Receptor Subtypes to Zinc Inhibition

1997 • 210 citations

Developmental changes in localization of NMDA receptor subunits in primary cultures of cortical neurons

1998 • 187 citations

Spontaneous synchronous synaptic calcium transients in cultured cortical neurons

1992 • 177 citations

Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific.

1996 • 172 citations

N-Terminal Domains in the NR2 Subunit Control Desensitization of NMDA Receptors

1998 • 164 citations

Differential regulation of synaptic and extra-synaptic NMDA receptors

2002 • 160 citations

cAMP-Dependent Protein Kinase Mediates Activity-Regulated Synaptic Targeting of NMDA Receptors

2001 • 140 citations

The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N -methyl- <scp>d</scp> -aspartate responses

1997 • 138 citations

Expression of mRNAs encoding subunits of the N-methyl-D-aspartate receptor in cultured cortical neurons.

1994 • 132 citations

Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A

2001 • 118 citations

AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity

1995 • 111 citations

Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors

2002 • 109 citations

Glycine-Independent NMDA Receptor Desensitization: Localization of Structural Determinants

1998 • 100 citations

Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches

1994 • 99 citations

Evidence That Actin Depolymerization Protects Hippocampal Neurons against Excitotoxicity by Stabilizing [Ca2+]i

1995 • 83 citations

Modulation of the Channel Activity of the ε2/ζ1-SubtypeN-Methyl d-Aspartate Receptor by PSD-95

1999 • 81 citations

Cyclothiazide Treatment Unmasks AMPA Excitotoxicity in Rat Primary Hippocampal Cultures

1993 • 67 citations

Blockade of desensitization augments quisqualate excitotoxicity in hippocampal neurons

1990 • 65 citations

Glutamate Receptor Ion Channel Properties Predict Vulnerability to Cytotoxicity in a Transfected Nonneuronal Cell Line

1996 • 49 citations

The Postsynaptic Density Protein PSD‐95 Differentially Regulates Insulin‐ and Src‐Mediated Current Modulation of Mouse NMDA Receptors Expressed in Xenopus Oocytes

2000 • 48 citations

Coexpression of Postsynaptic Density‐95 Protein with NMDA Receptors Results in Enhanced Receptor Expression Together with a Decreased Sensitivity to L‐Glutamate

2000 • 45 citations

The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons

1997 • 34 citations

Prostacyclin‐induced rundown of N‐methyl‐<scp>d</scp>‐aspartate receptor currents in HEK293 cells is protein kinase A‐dependent and NR2 subunit‐selective

2002 • 3 citations