Activation and desensitization of N‐methyl‐D‐aspartate receptors in nucleated outside‐out patches from mouse neurones.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

1957 • 1,457 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1980 • 608 citations

Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents

1990 • 570 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

The action of N‐methyl‐D‐aspartic acid on mouse spinal neurones in culture.

1985 • 417 citations

Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine

1989 • 408 citations

Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices

1990 • 396 citations

Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

1991 • 333 citations

Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo III

1987 • 288 citations

Kinetic analysis of interactions between kainate and AMPA: Evidence for activation of a single receptor in mouse hippocampal neurons

1991 • 263 citations

On the mechanism of desensitization at cholinergic receptors.

1970 • 247 citations

Quisqualate Activates a Rapidly Inactivating High Conductance Ionic Channel in Hippocampal Neurons

1989 • 237 citations

N‐methyl‐D‐aspartate‐activated channels of mouse central neurones in magnesium‐free solutions.

1988 • 230 citations

Regulation of N‐methyl‐D‐aspartate receptors revealed by intracellular dialysis of murine neurones in culture.

1989 • 225 citations

Pharmacological properties and H+ sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones.

1991 • 221 citations

A kinetic analysis of the modulation of N‐methyl‐D‐aspartic acid receptors by glycine in mouse cultured hippocampal neurones.

1990 • 216 citations

Desensitization at the frog neuromuscular junction: a biphasic process

1982 • 211 citations

Modulation of N‐methyl‐D‐aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones.

1990 • 199 citations

Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

1991 • 198 citations

6,7-Dinitro-quinoxaline-2,3-dion and 6-nitro,7-cyano-quinoxaline-2,3-dion antagonise responses to NMDA in the rat spinal cord via an action at the strychnine-insensitive glycine receptor

1988 • 197 citations

Glycine is a coagonist at the NMDA receptor/channel complex

1990 • 172 citations

Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.

1988 • 146 citations

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N‐methyl‐D‐aspartate receptor.

1990 • 139 citations

Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization

1982 • 135 citations

Glycine decreases desensitization of N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses.

1990 • 117 citations

Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons

1990 • 109 citations

Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata

1983 • 108 citations

Glutamate activation of a single NMDA receptorchannel produces a cluster of channel openings

1991 • 99 citations

The effect of agonist concentration, membrane voltage and calcium on n-methyl-d-aspartate receptor desensitization

1990 • 98 citations

Desensitization of the acetylcholine receptor of frog end‐plates measured in a Vaseline‐gap voltage clamp.

1989 • 97 citations

Rapid activation, desensitization, and resensitization of synaptic channels of crayfish muscle after glutamate pulses

1990 • 97 citations

A method for making solution changes in the sub-millisecond range at the tip of a patch pipette

1989 • 82 citations

Direct measurement of the concentration- and time-dependent open probability of the nicotinic acetylcholine receptor channel

1990 • 75 citations

Excision of membrane patches reduces the mean open time of nicotinic acetylcholine receptors

1990 • 39 citations

Steep concentration dependence and fast desensitization of nicotinic channel currents elicited by acetylcholine pulses, studied in adult vertebrate muscle

1991 • 37 citations

Glycine-insensitive desensitization of N- receptors in acutely isolated mammalian central neurons

1990 • 33 citations

The pharmacological specificity of N‐methyl‐<scp>d</scp>‐aspartate receptors in rat cerebral cortex: correspondence between radioligand binding and electrophysiological measurements

1991 • 26 citations

Human nicotinic acetylcholine receptor: the influence of second messengers on activation and desensitization

1990 • 26 citations

mRNA from NCB-20 cells encodes the N-methyl-D-aspartate/phencyclidine receptor: a Xenopus oocyte expression study.

1989 • 23 citations

Properties of the nicotinic-receptor-activated current in adrenal chromaffin cells of the guinea-pig

1991 • 20 citations

Desensitization of NMDA receptors does not proceed in the presence of kynurenate

1990 • 9 citations