Selective phosphorylation of the alpha subunit of the sodium channel by cAMP-dependent protein kinase.

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels

1980 • 3,334 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes

1980 • 1,236 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASES, IV. WIDESPREAD OCCURRENCE OF ADENOSINE 3′,5′-MONOPHOSPHATE-DEPENDENT PROTEIN KINASE IN VARIOUS TISSUES AND PHYLA OF THE ANIMAL KINGDOM

1969 • 775 citations

Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters†

1976 • 694 citations

Effects of potassium, veratridine, and scorpion venom on calcium accumulation and transmitter release by nerve terminals in vitro.

1975 • 559 citations

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.

1980 • 380 citations

Mechanism of calcium current modulation underlying presynaptic facilitation and behavioral sensitization in Aplysia.

1980 • 363 citations

Isolation of phosphorylated peptides and proteins on ion exchange papers

1978 • 359 citations

Regulation of Endogenous Phosphorylation of Specific Proteins in Synaptic Membrane Fractions from Rat Brain by Adenosine 3′:5′-Monophosphate

1973 • 341 citations

Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase.

1977 • 328 citations

Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture

1980 • 306 citations

Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.

1978 • 270 citations

Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues.

1977 • 270 citations

Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3',5'-monophosphate dependent protein kinases

1977 • 264 citations

Purification of the saxitoxin receptor of the sodium channel from rat brain.

1981 • 223 citations

Histamine-sensitive adenylate cyclase in mammalian brain

1976 • 218 citations

Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes.

1979 • 214 citations

Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin.

1980 • 199 citations

A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves.

1976 • 195 citations

Serotonin-induced hyperpolarization of an indentified Aplysia neuron is mediated by cyclic AMP.

1980 • 133 citations

Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel.

1980 • 129 citations

Crosslinking of iodine-125-labeled calcium-dependent regulatory protein to the calcium(2+) ion-sensitive phosphodiesterase purified from bovine heart

1979 • 129 citations

Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophoruselectricus

1980 • 113 citations

Phosphorylation of synthetic peptide analogs of rabbit cardiac troponin inhibitory subunit by the cyclic AMP-dependent protein kinase.

1979 • 77 citations

Selection of variant neuroblastoma clones with missing or altered sodium channels.

1979 • 19 citations