Down syndrome: molecular mapping of the congenital heart disease and duodenal stenosis.

Variable Number of Tandem Repeat (VNTR) Markers for Human Gene Mapping

1987 • 1,683 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

High Resolution of Human Chromosomes

1976 • 786 citations

Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome.

1989 • 261 citations

Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype.

1990 • 241 citations

Molecular genetic approach to the characterization of the ?Down syndrome region? of chromosome 21

1989 • 195 citations

Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA.

1983 • 193 citations

Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.

1990 • 187 citations

Down's syndrome

1974 • 134 citations

Trisomy 16 in the mouse fetus associated with generalized edema and cardiovascular and urinary tract anomalies

1982 • 129 citations

Isolation of polymorphic DNA fragments from human chromosome 4

1987 • 100 citations

Cloned DNA probes regionally mapped to human Chromosome 21 and their use in determining the origin of nondisjunction

1985 • 93 citations

Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17.

1988 • 76 citations

The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21

1989 • 63 citations

The Alzheimer amyloid precursor protein maps to human chromosome 21 bands q21.105–q21.05

1989 • 57 citations

Isolation and regional mapping of DNA sequences unique to human chromosome 21.

1987 • 45 citations

[Partial trisomy 21 (21q21 - 21q22.2)].

1976 • 43 citations

Physical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21.

1990 • 41 citations

Free proximal trisomy 21 without the Down syndrome

1987 • 32 citations

A boy with Down's syndrome having recombinant chromosome 21 but no SOD‐1 excess

1987 • 21 citations

RFLPs at the D21S19 locus of human chromosome 21

1985 • 11 citations