Human interferon-gamma is internalized and degraded by cultured fibroblasts.

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Lysosomotropic agents

1974 • 1,887 citations

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

1974 • 1,481 citations

The Interferon System

1979 • 1,035 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

The biochemistry of glycoproteins and proteoglycans

1980 • 651 citations

Evidence that types I and II interferons have different receptors

1981 • 511 citations

Membrane Receptors and Hormone Action

1976 • 484 citations

Production of High-Titered Interferon in Cultures of Human Diploid Cells

1972 • 471 citations

Clearance and binding of two electrophoretic “fast” forms of human alpha 2-macroglobulin.

1981 • 398 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions.

1979 • 232 citations

Primary amines inhibit recycling of α2M receptors in fibroblasts

1980 • 213 citations

Peptide Hormone-Induced Receptor Mobility, Aggregation, and Internalization

1981 • 207 citations

Polypeptide-Binding Membrane Receptors: Analysis and Classification

1981 • 195 citations

Specific binding of 125I-human interferon-gamma to high affinity receptors on human fibroblasts.

1982 • 165 citations

Protein transport: A selective membrane mechanism

1976 • 161 citations

Partial purification and characterization of human gamma (immune) interferon.

1981 • 145 citations

Galactose-specific recognition system of mammalian liver: receptor distribution on the hepatocyte cell surface.

1981 • 129 citations

Interaction of interferon with cellular receptors. Internalization and degradation of cell-bound interferon.

1982 • 125 citations

Surface binding and rates of internalization of 125I-insulin in adipocytes and IM-9 lymphocytes.

1982 • 116 citations

Molecular Weight of Human Gamma Interferon Is Similar to that of Other Human Interferons

1982 • 102 citations

Evidence for different pathways for the degradation of insulin and insulin receptor in the chick liver cell.

1982 • 93 citations

Purification of two subspecies of human gamma (immune) interferon.

1982 • 90 citations

Analysis of the effect of amines on inhibition of receptor-mediated and fluid-phase pinocytosis in rabbit alveolar macrophages

1981 • 88 citations

Specific binding of human alpha interferon to a high affinity cell surface binding site on bovine kidney cells.

1982 • 80 citations

Protein mediated vitamin uptake

1979 • 73 citations

Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway.

1980 • 72 citations

Immune Interferon Activates Cells More Slowly Than Does Virus-Induced Interferon

1978 • 67 citations

Effect of primary amines on interferon action

1982 • 26 citations