Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

1973 • 2,955 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.

1975 • 705 citations

The extinction coefficient of cytochrome c

1962 • 693 citations

RECEPTORS FOR COMPLEMENT ON LEUKOCYTES

1968 • 684 citations

Metalloenzymes and myocardial infarction. II. Malic and lactic dehydrogenase activities and zinc concentrations in serum.

1956 • 669 citations

Evidence that Peroxidation of Lysosomal Membranes Is Initiated by Hydroxyl Free Radicals Produced during Flavin Enzyme Activity

1973 • 663 citations

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION

1974 • 567 citations

The immunologic release of constituents from neutrophil leukocytes. I. The role of antibody and complement on nonphagocytosable surfaces or phagocytosable particles.

1971 • 513 citations

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM LEUKOCYTES EXPOSED TO IMMUNE COMPLEXES AND OTHER PARTICLES

1971 • 439 citations

Defective Superoxide Production by Granulocytes from Patients with Chronic Granulomatous Disease

1974 • 375 citations

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes: Microtubule Assembly and Membrane Fusion Induced by a Component of Complement

1973 • 329 citations

Biological Defense Mechanisms THE EFFECT OF BACTERIA AND SERUM ON SUPEROXIDE PRODUCTION BY GRANULOCYTES

1974 • 309 citations

An Abnormality of the Alternate Pathway of Complement Activation in Sickle-Cell Disease

1973 • 275 citations

Superoxide Dismutases in Polymorphonuclear Leukocytes

1974 • 271 citations

Quantitative aspects of the production of superoxide radicals by phagocytizing human granulocytes.

1975 • 265 citations

Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysis

1972 • 258 citations

Superoxide production by phagocytic leukocytes.

1975 • 257 citations

Receptors for human γG Globulin on human neutrophils

1970 • 250 citations

Cytochalasin B: Effect on Lysosomal Enzyme Release from Human Leukocytes

1973 • 243 citations

A Preparative method for the separation of 7s gamma globulin from human serum

1964 • 243 citations

STUDIES ON LYSOSOMES

1968 • 238 citations

Role of myeloperoxidase-mediated antimicrobial systems in intact leukocytes.

1972 • 236 citations

The influence of phorbol myristate acetate on oxygen consumption by polymorphonuclear leukocytes.

1974 • 230 citations

FORMATION OF C3a AND C5a ANAPHYLATOXINS IN WHOLE HUMAN SERUM AFTER INHIBITION OF THE ANAPHYLATOXIN INACTIVATOR

1973 • 204 citations

Biological defense mechanisms. Evidence for the participation of superoxide in bacterial killing by xanthine oxidase.

1975 • 202 citations

Singlet Excited Oxygen as a Mediator of the Antibacterial Action of Leukocytes

1974 • 190 citations

Lysosomal Enzyme Release from Human Leukocytes: Mediation by the Alternate Pathway of Complement Activation

1973 • 188 citations

Cytochalasin B reversibly inhibits phagocytosis: functional, metabolic, and ultrastructural effects in human blood leukocytes and rabbit alveolar macrophages.

1971 • 187 citations

The adherence of leucocytes and platelets induced by fixed IgG antibody or complement.

1969 • 186 citations

Cytochalasin B: Inhibition of D-2-Deoxyglucose Transport into Leukocytes and Fibroblasts

1972 • 166 citations

Specific degranulation of human polymorphonuclear leukocytes

1974 • 162 citations

Role of the Superoxide Anion in the Myeloperoxidase-mediated Antimicrobial System

1974 • 153 citations

The Release of Granule Enzymes from Human Neutrophils Stimulated by Aggregated Immunoglobulins of Different Classes and Subclasses

1972 • 147 citations

Cytochalasin B III. Inhibition of Human Polymorphonuclear Leukocyte Phagocytosis

1971 • 136 citations

Effects of Phorbol Myristate Acetate on the Metabolism and Ultrastructure of Neutrophils in Chronic Granulomatous Disease

1974 • 127 citations

Selective labilization of specific granules in polymorphonuclear leukocytes by phorbol myristate acetate.

1974 • 118 citations

Superoxide Dismutase Activity in Leukocytes

1974 • 116 citations

Cytochalasin B: Effects on Microfilaments and Movement of Melanin Granules within Melanocytes

1972 • 114 citations

Interaction of immunoglobulins with liposomes.

1974 • 98 citations

POTASSIUM AND AMINO ACID TRANSPORT IN HUMAN LEUKOCYTES EXPOSED TO PHAGOCYTIC STIMULI

1974 • 69 citations

Enhancement of Nitroblue Tetrazolium Dye Reduction by Leukocytes Exposed to a Component of Complement in the Absence of Phagocytosis

1975 • 43 citations

Effect of specific antibodies on the metabolism of guinea pig polymorphonuclear leukocytes.

1971 • 28 citations

The visualization of receptors for the Fc portion of the IgG molecule on human neutrophil leukocytes

1974 • 17 citations

Influence of Type of Ingested Particle on Human Leukocyte Metabolism

1971 • 14 citations

Polymorphonuclear Leukocyte Activation: Effects of Phospholipase C

1972 • 13 citations

Carbohydte metabolism in leukocytes. XI. Stimulation of eosinophils and neutrophils.

1969 • 10 citations

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