Potentiation of Tumor Necrosis Factor-Induced NF-κB Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IκBα

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Missing Pieces in the NF-κB Puzzle

2002 • 3,560 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

1998 • 1,200 citations

Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

2001 • 1,193 citations

Series Introduction: The transcription factor NF-κB and human disease

2001 • 984 citations

The Phosphorylation Status of Nuclear NF-ΚB Determines Its Association with CBP/p300 or HDAC-1

2002 • 934 citations

The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism

1997 • 820 citations

CREB-binding protein/p300 are transcriptional coactivators of p65

1997 • 819 citations

IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain

1999 • 812 citations

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB

2002 • 777 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

2000 • 720 citations

The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression

2001 • 708 citations

p38-dependent marking of inflammatory genes for increased NF-κB recruitment

2001 • 692 citations

Regulation of activity of the transcription factor GATA-1 by acetylation

1998 • 686 citations

Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

1996 • 571 citations

Post-activation Turn-off of NF-κB-dependent Transcription Is Regulated by Acetylation of p65

2003 • 502 citations

Transcriptional Activation by NF-κB Requires Multiple Coactivators

1999 • 433 citations

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

1998 • 433 citations

Nuclear localization of IκBα promotes active transport of NF-κB from the nucleus to the cytoplasm

1997 • 405 citations

The IKK complex: an integrator of all signals that activate NF-κB?

2000 • 400 citations

Regulatory functions of ubiquitination in the immune system

2002 • 392 citations

Two Waves of Nuclear Factor κb Recruitment to Target Promoters

2001 • 386 citations

The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter

1999 • 354 citations

Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways

2001 • 321 citations

Acetylation of HMG I(Y) by CBP Turns off IFNβ Expression by Disrupting the Enhanceosome

1998 • 321 citations

Involvement of Valosin-containing Protein, an ATPase Co-purified with IκBα and 26 S Proteasome, in Ubiquitin-Proteasome-mediated Degradation of IκBα

1998 • 317 citations

Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit

2002 • 305 citations

Butyrate Suppression of Colonocyte NF-κB Activation and Cellular Proteasome Activity

2001 • 266 citations

Crucial Role of the Amino-Terminal Tyrosine Residue 42 and the Carboxyl-Terminal PEST Domain of IκBα in NF-κB Activation by an Oxidative Stress

2000 • 251 citations

Nuclear Retention of IκBα Protects It from Signal-induced Degradation and Inhibits Nuclear Factor κB Transcriptional Activation

1999 • 232 citations

Steroid Receptor Coactivator-1 Interacts with the p50 Subunit and Coactivates Nuclear Factor κB-mediated Transactivations

1998 • 232 citations

Sodium valproate inhibits production of TNF-α and IL-6 and activation of NF-κB

2000 • 183 citations

Wnt/β-Catenin Signaling Induces the Expression and Activity of βTrCP Ubiquitin Ligase Receptor

2000 • 181 citations

Age-related alterations of proteasome structure and function in aging epidermis

2000 • 177 citations

HATs on and beyond chromatin

2001 • 174 citations

Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).

1993 • 135 citations

Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 Promoter

1998 • 134 citations

Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptors, as a Novel Transcriptional Corepressor Molecule of Activating Protein-1, Nuclear Factor-κB, and Serum Response Factor

2000 • 129 citations

Domain Organization of IκBα and Sites of Interaction with NF-κB p65

1995 • 124 citations

Activation of Human Immunodeficiency Virus Transcription in T Cells Revisited: NF-κB p65 Stimulates Transcriptional Elongation

2001 • 124 citations

Characterization of IκBα Nuclear Import Pathway

1999 • 116 citations

Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors.

1998 • 101 citations

The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells.

1999 • 96 citations

Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin.

1999 • 87 citations

Superinduction of IL-8 in T Cells by HIV-1 Tat Protein Is Mediated Through NF-κB Factors

1998 • 75 citations

Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB

2001 • 71 citations

The transcription of the intercellular adhesion molecule-1 is regulated by Ets transcription factors

1998 • 64 citations

Dimerization of NF-KB2 with RelA(p65) Regulates DNA Binding, Transcriptional Activation, and Inhibition by an IκB-α (MAD-3)

1993 • 43 citations

Upstream Stimulatory Factors Binding to an E Box Motif in the R Region of the Bovine Leukemia Virus Long Terminal Repeat Stimulates Viral Gene Expression

2002 • 40 citations

Heterodimeric retinoic acid receptor-beta and retinoid X receptor-alpha complexes stimulate expression of the intercellular adhesion molecule-1 gene.

1995 • 23 citations

Trichostatin A-Mediated Regulation of Gene Expression and Protein Kinase Activities: Reprogramming Tumor Cells for Ribotoxic Stress-Induced Apoptosis

2000 • 18 citations