Trichostatin A-Mediated Regulation of Gene Expression and Protein Kinase Activities: Reprogramming Tumor Cells for Ribotoxic Stress-Induced Apoptosis

Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function

1995 • 719 citations

The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.

1996 • 662 citations

Escaping Cell Death: Survival Proteins in Cancer

1999 • 629 citations

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27

1999 • 497 citations

HSP27 inhibits cytochrome c‐dependent activation of procaspase‐9

1999 • 496 citations

Histone Deacetylase Inhibitor Activates the WAF1/Cip1 Gene Promoter through the Sp1 Sites

1997 • 291 citations

Response of human breast cancer cells to heat shock and chemotherapeutic drugs.

1992 • 247 citations

HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs.

1997 • 238 citations

Coupling of Cell Growth Control and Apoptosis Functions of Id Proteins

1998 • 187 citations

Spontaneous Neutrophil Apoptosis Involves Caspase 3-mediated Activation of Protein Kinase C-δ

1999 • 186 citations

p300 Collaborates with Sp1 and Sp3 in p21 / Promoter Activation Induced by Histone Deacetylase Inhibitor

2000 • 169 citations

A Role for HSP27 in Sensory Neuron Survival

1999 • 162 citations

Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor.

1999 • 148 citations

Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells

1999 • 132 citations

Activation of Androgen Receptor Function by a Novel Nuclear Protein Kinase

1998 • 118 citations

Id2 Promotes Apoptosis by a Novel Mechanism Independent of Dimerization to Basic Helix-Loop-Helix Factors

1998 • 113 citations

Differential Expression of Human Histone Deacetylase mRNAs in Response to Immune Cell Apoptosis Induction by Trichostatin A and Butyrate

1998 • 99 citations

Calmodulin‐dependent protein kinase II mediates signal transduction in apoptosis

1997 • 84 citations

Trichostatin A Modulates Expression of p21waf1/cip1, Bcl-xL, ID1, ID2, ID3, CRAB2, GATA-2, hsp86 and TFIID/TAFII31 mRNA in Human Lung Adenocarcinoma Cells

2000 • 51 citations

Changes in Protein Kinase C Isoenzyme Expression Associated with Apoptosis in U937 Myelomonocytic Cells

1995 • 47 citations

Effects of Cell Density and Trichostatin A on the Expression ofHDAC1andp57Kip2in Hep 3B Cells

1998 • 46 citations

Modulating IGFBP-3 expression by trichostatin A: potential therapeutic role in the treatment of hepatocellular carcinoma.

2000 • 35 citations

A possible role for PKCδ in cerebellar granule cells apoptosis

1998 • 34 citations

Trichostatin A and Herboxidiene Up-regulate the Gene Expression of Low Density Lipoprotein Receptor.

1997 • 34 citations

Murine Cells Transfected with Human Hsp27 cDNA Resist TNF-Induced Cytotoxicity

1996 • 28 citations

Suppression of adenovirus E1A-induced apoptosis by mutated p53 is overcome by coexpression with Id proteins

1998 • 25 citations

Sensitization of tumor cells to ribotoxic stress-induced apoptotic cell death: a new therapeutic strategy.

1999 • 23 citations

Doppa induces cell death but not differentiation of U937 cells: Evidence for the involvement of PKC-βl in the regulation of apoptosis

1996 • 21 citations