Purification and characterization of a processing protease from rat liver mitochondria.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers.

1986 • 493 citations

Two nuclear mutations that block mitochondrial protein import in yeast.

1984 • 490 citations

Import of proteins into mitochondria: precursor forms of the extramitochondrially made F1-ATPase subunits in yeast.

1979 • 455 citations

How mitochondria import proteins

1984 • 405 citations

Mitochondrial protein import: Identification of processing peptidase and of PEP, a processing enhancing protein

1988 • 388 citations

Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria.

1982 • 351 citations

Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase

1986 • 340 citations

Purification of microsomal signal peptidase as a complex.

1986 • 313 citations

Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into Mitochondsria

1982 • 292 citations

Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent.

1982 • 254 citations

A leader peptide is sufficient to direct mitochondrial import of a chimeric protein.

1985 • 239 citations

Purification and characterization of leader (signal) peptidase from Escherichia coli.

1980 • 237 citations

Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria.

1982 • 220 citations

Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes.

1988 • 219 citations

Import of proteins into mitochondria. Partial purification of a matrix-located protease involved in cleavage of mitochondrial precursor polypeptides.

1983 • 201 citations

The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix

1984 • 199 citations

Protein unfolding and the energetics of protein translocation across biological membranes

1988 • 192 citations

MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease.

1988 • 181 citations

Energy-dependent processing of cytoplasmically made precursors to mitochondrial proteins.

1979 • 171 citations

A neutral metallo endoprotease involved in the processing of an F1-ATPase subunit precursor in mitochondria.

1982 • 167 citations

Assembly of Cytochrome c. Apocytochrome c Is Bound to Specific Sites on Mitochondria before Its Conversion to Holocytochrome c

1981 • 157 citations

Processing peptidase of Neurospora mitochondria. Two-step cleavage of imported ATPase subunit 9

1984 • 157 citations

The processing peptidase of yeast mitochondria: the two co-operating components MPP and PEP are structurally related.

1988 • 152 citations

Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit.

1988 • 149 citations

Processing of pre-ornithine transcarbamylase requires a zinc-dependent protease localized to the mitochondrial matrix

1982 • 124 citations

Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes.

1988 • 122 citations

Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide.

1985 • 120 citations

Biogenesis of mitochondrial ubiquinol:cytochrome c reductase (cytochrome bc1 complex). Precursor proteins and their transfer into mitochondria.

1982 • 117 citations

A Mitochondria1 Protease that Cleaves the Precursor of Ornithine Carbamoyltransferase

1982 • 110 citations

A yeast mutant temperature-sensitive for mitochondrial assembly is deficient in a mitochondrial protease activity that cleaves imported precursor polypeptides.

1985 • 107 citations

Requirement for metalloendoprotease in exocytosis: Evidence in mast cells and adrenal chromaffin cells

1985 • 100 citations

Transfer of proteins into mitochondria. Precursor to the ADP/ATP carrier binds to receptor sites on isolated mitochondria.

1983 • 98 citations

Precursor proteins are transported into mitochondria in the absence of proteolytic cleavage of the additional sequences.

1983 • 95 citations

Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells.

1981 • 75 citations

Effects of Synthetic Model Peptides Resembling the Extension Peptides of Mitochondrial Enzyme Precursors on Import of the Precursors into Mitochondria1

1985 • 75 citations

Specific Binding of Mitochondrial Protein Precursors to Liposomes Containing Cardiolipin1

1988 • 69 citations

Rat liver L-glutamate dehydrogenase, malate dehydrogenase, D-beta-hydroxybutyrate dehydrogenase, and sulfite oxidase are each synthesized as larger precursors by cytoplasmic free polysomes.

1982 • 60 citations

In vitro synthesis of adrenodoxin and adrenodoxin reductase: Existence of a putative large precursor form of adrenodoxin

1980 • 51 citations

Cleavage of honeybee prepromelittin by an endoprotease from rat liver microsomes: identification of intact signal peptide.

1982 • 46 citations

Newly processed ornithine transcarbamylase subunits are assembled to trimers in rat liver mitochondria.

1984 • 45 citations

Processing-Independent In Vitro Translocation of Cytochrome P-450(SCC) Precursor across Mitochondrial Membranes1

1986 • 41 citations

Import of proteins into mitochondria. Isolated yeast mitochondria and a solubilized matrix protease correctly process cytochrome c oxidase subunit V precursor at the NH2 terminus.

1983 • 40 citations

Import of the malate dehydrogenase precursor by mitochondria. Cleavage within leader peptide by matrix protease leads to formation of intermediate-sized form.

1988 • 38 citations

Import and Processing of the Precursor of Cytochrome P-450(SCC) by Bovine Adrenal Cortex Mitochondria1

1985 • 37 citations

Partial Purification of a Metalloprotease Catalyzing the Processing of Adrenodoxin Precursor in Bovine Adrenal Cortex Mitochondria

1984 • 35 citations

In vitro synthesis of mitochondrial cytochromes P-450(scc) and P-450(11-β) and microsomal cytochrome P-450(C-21) by both free and bound polysomes isolated from bovine adrenal cortex

1980 • 33 citations

Mitochondrial import and processing of mutant human ornithine transcarbamylase precursors in cultured cells.

1988 • 26 citations

Transport of the Precursor for Sulfite Oxidase into Intermembrane Space of Liver Mitochondria: Characterization of Import and Processing Activities1

1984 • 21 citations

Synthetic Partial Extension Peptides of P-450(SCC)and Adrenodoxin Precursors: Effects on the Import of Mitochondrial Enzyme Precursors

1987 • 21 citations

Characterization of a Mitochondrial Matrix Protease Catalyzing the Processing of Adrenodoxin Precursor1

1986 • 20 citations

Metalloendoprotease inhibitors block protein synthesis, intracellular transport, and endocytosis in hepatoma cells.

1988 • 18 citations

Chymotrypsin substrate analogues inhibit endocytosis of insulin and insulin receptors in adipocytes.

1986 • 17 citations

Transport of the Precursor for Sulfite Oxidase into Intermembrane Space of Liver Mitochondria: Binding of the Precursor to Outer Mitochondrial Membrane

1984 • 13 citations

Mitochondrial Import and Processing of Mutant Human Ornithine Transcarbamylase Precursors in Cultured Cells

1988 • 11 citations

Purification and Characterization of a Signal Peptide, a Product of Protein Secretion across the Cytoplasmic Membrane of Escherichia coli1

1988 • 4 citations

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