Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes.

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

How mitochondria import proteins

1984 • 405 citations

Mitochondrial protein import: Identification of processing peptidase and of PEP, a processing enhancing protein

1988 • 388 citations

Structure and Expression of a Complementary DNA for the Nuclear Coded Precursor of Human Mitochondrial Ornithine Transcarbamylase

1984 • 279 citations

The first twelve amino acids (less than half of the pre-sequence) of an imported mitochondrial protein can direct mouse cytosolic dihydrofolate reductase into the yeast mitochondrial matrix.

1985 • 279 citations

The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal.

1986 • 258 citations

A leader peptide is sufficient to direct mitochondrial import of a chimeric protein.

1985 • 239 citations

The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.

1984 • 236 citations

MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease.

1988 • 181 citations

Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein.

1984 • 154 citations

A rapid and simple procedure to deplete rat-liver mitochondria of lysosomal activity

1970 • 129 citations

Processing of pre-ornithine transcarbamylase requires a zinc-dependent protease localized to the mitochondrial matrix

1982 • 124 citations

A Mitochondria1 Protease that Cleaves the Precursor of Ornithine Carbamoyltransferase

1982 • 110 citations

Energy-dependent translocation of the precursor of ornithine transcarbamylase by isolated rat liver mitochondria.

1982 • 78 citations

Import of rat ornithine transcarbamylase precursor into mitochondria: two-step processing of the leader peptide.

1987 • 76 citations

Characterization of a protease apparently involved in processing of pre-ornithine transcarbamylase of rat liver.

1980 • 71 citations

Posttranslational uptake and processing of in vitro synthesized ornithine transcarbamoylase precursor by isolated rat liver mitochondria.

1981 • 70 citations

Uptake and processing of the precursor for rat liver ornithine transcarbamylase by isolated mitochondria. Inhibition by uncouplers.

1981 • 56 citations

Coding sequence of the precursor of the beta subunit of rat propionyl-CoA carboxylase.

1986 • 54 citations

Newly processed ornithine transcarbamylase subunits are assembled to trimers in rat liver mitochondria.

1984 • 45 citations

A metalloprotease involved in the processing of mitochondrial precursor proteins

1986 • 40 citations

Import of the malate dehydrogenase precursor by mitochondria. Cleavage within leader peptide by matrix protease leads to formation of intermediate-sized form.

1988 • 38 citations

The role of arginine residues in the rat mitochondrial malate dehydrogenase transit peptide.

1987 • 36 citations

Targeting of Nuclear-Encoded Proteins to the Mitochondrial Matrix: Implications for Human Genetic Defects

1986 • 27 citations