Chapter 9 NMDA receptors and AMPA/kainate receptors mediate parallel injury in cerebral cortical cultures subjected to oxygen-glucose deprivation

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

The physiology of excitatory amino acids in the vertebrate central nervous system

1987 • 1,718 citations

Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

1989 • 1,237 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Excitotoxity and the NMDA receptor

1987 • 1,053 citations

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1989 • 987 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

Cerebral hypoxia: some new approaches and unanswered questions

1990 • 674 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

Free Radicals and Brain Damage

1993 • 527 citations

Selective modulation of NMDA responses by reduction and oxidation

1989 • 459 citations

Glutamate receptor channels: novel properties and new clones

1992 • 427 citations

Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures

1990 • 372 citations

Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury

1987 • 334 citations

Delayed neurotoxicity of excitatory amino acids In vitro

1987 • 332 citations

Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

1990 • 302 citations

Methods for antagonizing glutamate neurotoxicity.

1990 • 277 citations

21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures

1990 • 248 citations

Calcium, Excitotoxins, and Neuronal Death in the Brain^a

1989 • 235 citations

Excitatory Amino Acid Release from Rat Hippocampal Slices as a Consequence of Free‐Radical Formation

1988 • 210 citations

Direct Evidence That Excitotoxicity in Cultured Neurons Is Mediated via N‐Methyl‐D‐Aspartate (NMDA) as well as Non‐NMDA Receptors

1989 • 208 citations

Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration

1986 • 204 citations

Mild acidosis protects hippocampal neurons from injury induced by oxygen and glucose deprivation

1990 • 202 citations

Do NMDA antagonists protect against cerebral ischemia: are clinical trials warranted?

1990 • 154 citations

Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose

1991 • 110 citations

Do NMDA Antagonists Prevent Neuronal Injury? Yes.

1992 • 94 citations

Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death

1991 • 91 citations

Cellular and molecular effects of polyunsaturated fatty acids in brain ischemia and injury

1985 • 85 citations

Requirement of NMDA receptor/channels for intracellular high-energy phosphates and the extent of intraneuronal calcium buffering in cultured mouse hippocampal neurons

1988 • 53 citations