A microsomal protein is involved in ATP-dependent transport of presecretory proteins into mammalian microsomes.
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References (46)
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Secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires ATP hydrolysis.
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The human glucose transporter can insert posttranslationally into microsomes
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M13 procoat and a pre-immunoglobulin share processing specificity but use different membrane receptor mechanisms.
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M13 procoat inserts into liposomes in the absence of other membrane proteins.
1985 • 121 citations
Assembly of translocation-competent proteoliposomes from detergent-solubilized rough microsomes
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Import of frog prepropeptide GLa into microsomes requires ATP but does not involve docking protein or ribosomes.
1987 • 111 citations
Chemical Synthesis and Enzymic Processing of Precursor Forms of Cecropins A and B
1989 • 109 citations
A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and post-translationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes.
1990 • 104 citations
Protein translocation across the yeast microsomal membrane is stimulated by a soluble factor.
1986 • 80 citations
In vivo and in vitro analysis of ptl1, a yeast ts mutant with a membrane-associated defect in protein translocation.
1988 • 79 citations
Import of honeybee prepromelittin into the endoplasmic reticulum: energy requirements for membrane insertion.
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Protein transport across the ER membrane
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Post-translational insertion of fragment of the glucose transporter into microsomes requires phosphoanhydride bond cleavage
1986 • 75 citations
The ATP requiring step in assembly of M13 procoat protein into microsomes is related to preservation of transport competence of the precursor protein.
1987 • 73 citations
Secretion in yeast: structural features influencing the post-translational translocation of prepro-alpha-factor in vitro.
1987 • 72 citations
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1990 • 66 citations
Preprotein conformation: the year's major theme in translocation studies
1988 • 63 citations
A membrane component of the endoplasmic reticulum that may be essential for protein translocation.
1989 • 61 citations
Evidence for the involvement of ATP in co-translational protein translocation
1987 • 52 citations
The ADP/ATP carrier from yeast (AAC‐2) is uniquely suited for the assignment of the binding center by photoaffinity labeling
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Reconstitution of protein translocation activity from partially solubilized microsomal vesicles.
1990 • 29 citations
Role of cytosolic factors in the transport of proteins across membranes.
1990 • 20 citations
Ribonucleoparticle-independent import of proteins into mammalian microsomes involves a membrane protein which is sensitive to chemical alkylation
1990 • 15 citations