A murine replication protein accumulates temporarily in the heterochromatic regions of nuclei prior to initiation of DNA replication

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

The localization of replication origins on ARS plasmids in S. cerevisiae

1987 • 1,051 citations

Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites.

1987 • 945 citations

Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase.

1985 • 640 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

The in vivo replication origin of the yeast 2μm plasmid

1987 • 437 citations

Yeast Origin Recognition Complex Functions in Transcription Silencing and DNA Replication

1993 • 435 citations

Isolation of ORC6 , a Component of the Yeast Origin Recognition Complex by a One-Hybrid System

1993 • 416 citations

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1993 • 400 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells.

1990 • 327 citations

A group of interacting yeast DNA replication genes.

1991 • 325 citations

Origin Recognition Complex (ORC) in Transcriptional Silencing and DNA Replication in S. cerevisiae

1993 • 314 citations

cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication.

1992 • 272 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

Yeast origin recognition complex is involved in DNA replication and transcriptional silencing

1993 • 231 citations

Subcellular localization of yeast CDC46 varies with the cell cycle.

1990 • 226 citations

Origins of DNA replication in metazoan chromosomes.

1993 • 203 citations

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor

1993 • 198 citations

Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.

1991 • 196 citations

High efficiency vectors for cosmid microcloning and genomic analysis

1989 • 190 citations

Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts

1991 • 170 citations

Cell cycle regulated phosphorylation of RPA-32 occurs within the replication initiation complex.

1992 • 154 citations

A question of time: Replication origins of eukaryotic chromosomes

1992 • 153 citations

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

1990 • 138 citations

Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein

1992 • 137 citations

Deletion mapping in human renal cell carcinoma.

1989 • 135 citations

Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A.

1992 • 134 citations

Fission yeastcdc21⁺belongs to a family of proteins involved in an early step of chromosome replication

1992 • 131 citations

The MCM2-3-5 proteins: are they replication licensing factors?

1994 • 124 citations

A human nuclear protein with sequence homology to a family of early s phase proteins is required for entry into s phase and for cell division

1994 • 120 citations

Intracellular localization and metabolism of DNA polymerase α in human cells visualized with monoclonal antibody

1984 • 115 citations

CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences.

1992 • 99 citations

Isolation of a large number of novel mammalian genes by a differential cDNA library sreening strategy

1991 • 97 citations

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mem replication proteins

1993 • 87 citations

Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor

1993 • 83 citations

Fission yeast genes nda1+ and nda4+, mutations of which lead to S-phase block, chromatin alteration and Ca2+ suppression, are members of the CDC46/MCM2 family.

1993 • 78 citations

Complete characterization of a large marker chromosome by reverse and forward chromosome painting

1992 • 56 citations

An S-phase specific release from a transcriptional block regulates the expression of mouse ribonucleotide reductase R2 subunit.

1992 • 53 citations

Intranuclear co-location of newly replicated DNA and PCNA by simultaneous immunofluorescent labelling and confocal microscopy in MCF-7 cells

1992 • 51 citations

Turning DNA replication on and off

1993 • 33 citations

Analysis of the expression of a large number of novel genes isolated from mouse prepubertal testis

1992 • 21 citations